Osteosarcoma (OS) is the most common type of primary solid tumor that develops in bone.
Although standard chemotherapy has significantly improved long‐term survival over the past …

Osteosarcoma is the most common type of solid bone cancer and the second leading cause
of cancer-related death in pediatric patients. Many patients are not cured by the current …

The aim of this paper was to design and fabricate a novel composite scaffold based on the
combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) …

Background Much attention has been recently focused on the role of cancer stem cells
(CSCs) in the initiation and progression of solid malignancies. Since CSCs are able to …

Osteosarcoma (OS) is one of the most prevalent malignant cancers with lower survival and
poor overall prognosis mainly in children and adolescents. Identifying the molecular …

MicroRNAs (miRNAs) have been implicated in the maintenance of the cancer stem cell
(CSC) phenotype via their ability to affect expression of genes and proteins that regulate cell …

High aldehyde dehydrogenase (ALDH) activity has recently been used to identify
tumorigenic cell fractions in many cancer types. Herein we hypothesized that a …

Osteosarcoma is a bone tumor, displaying significant cellular and histological heterogeneity
and a complex genetic phenotype. Although multiple studies strongly suggest the presence …

Magnetic hyperthermia is a potential technique for cancer therapy that exploits heat
generated by magnetic nanoparticles to kill cancerous cells. Many studies have shown that …

Previous studies have demonstrated that pluripotency-associated transcription factors, such
as Oct3/4, Nanog and Sox2, play a crucial role in the development and malignant …