Measuring changes in Plasmodium falciparum transmission: precision, accuracy and costs of metrics

LS Tusting, T Bousema, DL Smith, C Drakeley - Advances in parasitology, 2014 - Elsevier
As malaria declines in parts of Africa and elsewhere, and as more countries move towards
elimination, it is necessary to robustly evaluate the effect of interventions and control …

Molecular approaches to determine the multiplicity of Plasmodium infections

D Zhong, C Koepfli, L Cui, G Yan - Malaria journal, 2018 - Springer
Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the
number of genetically distinct parasite strains co-infecting a single host, which is an …

[HTML][HTML] Safety and differential antibody and T-cell responses to the Plasmodium falciparum sporozoite malaria vaccine, PfSPZ vaccine, by age in Tanzanian adults …

SA Jongo, LWP Church, AT Mtoro… - The American journal …, 2019 - ncbi.nlm.nih.gov
In 2016, there were more cases and deaths caused by malaria globally than in 2015. An
effective vaccine would be an ideal additional tool for reducing malaria's impact. Sanaria® …

Genetic Diversity of Plasmodium falciparum Populations in Malaria Declining Areas of Sabah, East Malaysia

MR Mohd Abd Razak, UR Sastu, NA Norahmad… - PloS one, 2016 - journals.plos.org
Malaysia has a national goal to eliminate malaria by 2020. Understanding the genetic
diversity of malaria parasites in residual transmission foci can provide invaluable information …

Genetic diversity of Plasmodium falciparum and genetic profile in children affected by uncomplicated malaria in Cameroon

TN Metoh, JH Chen, P Fon-Gah, X Zhou… - Malaria Journal, 2020 - Springer
Background Malaria is a major public health problem in Cameroon. The study of the genetic
diversity within parasite population is essential for understanding the mechanism underlying …

Seasonal variations in Plasmodium falciparum genetic diversity and multiplicity of infection in asymptomatic children living in southern Ghana

J Adjah, B Fiadzoe, R Ayanful-Torgby… - BMC Infectious …, 2018 - Springer
Abstract Background Genetic diversity in Plasmodium falciparum (P. falciparum) parasites is
a major hurdle to the control of malaria. This study monitored changes in the genetic …

Genetic diversity of Plasmodium falciparum isolates based on MSP-1 and MSP-2 genes from Kolla-Shele area, Arbaminch Zuria District, southwest Ethiopia

H Mohammed, T Mindaye, M Belayneh, M Kassa… - Malaria journal, 2015 - Springer
Background The genetic diversity of Plasmodium falciparum has been extensively studied in
various countries. However, limited data are available from Ethiopia. This study was …

A multiplex qPCR approach for detection of pfhrp2 and pfhrp3 gene deletions in multiple strain infections of Plasmodium falciparum

T Schindler, AC Deal, M Fink, E Guirou, KA Moser… - Scientific reports, 2019 - nature.com
The rapid and accurate diagnosis of Plasmodium falciparum malaria infection is an essential
factor in malaria control. Currently, malaria diagnosis in the field depends heavily on using …

Severe oxidative stress in sickle cell disease patients with uncomplicated Plasmodium falciparum malaria in Kampala, Uganda

SM Atiku, N Louise, DM Kasozi - BMC Infectious Diseases, 2019 - Springer
Background Oxidative stress plays a vital role in the pathogenesis of both Sickle Cell
Disease (SCD) and Plasmodium falciparum malaria. However, there are limited studies on …

Genetic diversity and complexity of Plasmodium falciparum infections in the microenvironment among siblings of the same household in North-Central Nigeria

SI Oyedeji, PU Bassi, SA Oyedeji, O Ojurongbe… - Malaria Journal, 2020 - Springer
Background Plasmodium falciparum parasites are known to exhibit extensive genetic
diversity in areas of high transmission intensity and infected individuals in such communities …