In-vitro and in-vivo assessment of nirmatrelvir penetration into CSF, central nervous system cells, tissues, and peripheral blood mononuclear cells
Three years after SARS-CoV-2 emerged as a global infectious threat, the virus has become
endemic. The neurological complications such as depression, anxiety, and other CNS …
endemic. The neurological complications such as depression, anxiety, and other CNS …
Trans-nasal brain delivery of anti-TB drugs by methyl-β-cyclodextrin microparticles show efficient mycobacterial clearance from central nervous system
Central nervous system tuberculosis (CNS-TB) is the most severe extra-pulmonary
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
A preclinical model of TB meningitis to determine drug penetration and activity at the sites of disease
F Lanni, R Antilus Sainte, M Hansen Jr… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Tuberculosis meningitis (TBM) is essentially treated with the first-line regimen used against
pulmonary tuberculosis, with a prolonged continuation phase. However, clinical outcomes …
pulmonary tuberculosis, with a prolonged continuation phase. However, clinical outcomes …
Preclinical assessment of nirmatrelvir penetration into cerebrospinal fluid and central nervous system cells and tissues
Three years after SARS-CoV-2 emerged as a global infectious threat, the virus has become
endemic. The neurological complications such as depression, anxiety, and other CNS …
endemic. The neurological complications such as depression, anxiety, and other CNS …
Central Nervous System Antiviral Pharmacology
SN Avedissian - 2024 - digitalcommons.unmc.edu
Soon after viral infection, viruses like Human Immunodeficiency Virus (HIV) and SARS-CoV-
2 can disseminate throughout the body and establish reservoirs in the central nervous …
2 can disseminate throughout the body and establish reservoirs in the central nervous …
[PDF][PDF] Pharmacokinetic Modelling of Rifampicin, Isoniazid, Pyrazinamide, Linezolid, and Rifabutin in
N Abdelgawad, JC Miranda, S Wasserman, F Lanni… - 1 - sntc.medicine.ufl.edu
Tuberculosis meningitis (TBM), the severest form of Mtb infection, has high mortality and
disability rates [1]. Current TBM treatments are derived from pulmonary TB protocols, without …
disability rates [1]. Current TBM treatments are derived from pulmonary TB protocols, without …