The formyl peptide receptors: diversity of ligands and mechanism for recognition
HQ He, RD Ye - Molecules, 2017 - mdpi.com
The formyl peptide receptors (FPRs) are G protein-coupled receptors that transduce
chemotactic signals in phagocytes and mediate host-defense as well as inflammatory …
chemotactic signals in phagocytes and mediate host-defense as well as inflammatory …
Antimicrobial activity and DFT studies of a novel set of spiropyrrolidines tethered with thiochroman-4-one/chroman-4-one scaffolds
N Chouchène, A Toumi, S Boudriga, H Edziri, M Sobeh… - Molecules, 2022 - mdpi.com
A novel series of 14 spiropyrrolidines bearing thiochroman-4-one/chroman-4-one, and
oxindole/acenaphthylene-1, 2-dione moieties were synthesized and characterized by …
oxindole/acenaphthylene-1, 2-dione moieties were synthesized and characterized by …
Flavonoids: from structure to health issues
C Santos-Buelga, AS Feliciano - Molecules, 2017 - mdpi.com
Flavonoids are one of the largest groups of plant secondary metabolites. They are
synthesized through the shikimate/phenylpropanoid and acetate/malonate pathways and …
synthesized through the shikimate/phenylpropanoid and acetate/malonate pathways and …
Light-Driven Two-Step Preparation of 4-Chromanone Fused to Estrone Derivatives
MI Quindt, GF Gola, JA Ramirez… - The Journal of Organic …, 2023 - ACS Publications
A protocol involving the irradiation of some 3-(2-alkenyl) estrone and 3-(2-alkenyl)-17-nor
estrone derivatives under a nitrogen atmosphere in organic solvents (both hexane and …
estrone derivatives under a nitrogen atmosphere in organic solvents (both hexane and …
Design, synthesis, molecular modeling and anticholinesterase activity of benzylidene-benzofuran-3-ones containing cyclic amine side chain
Aim: A series of 2-benzylidene-benzofuran-3-ones were designed from the structures of
Ebselen analogs and aurone derivatives and synthesized in good yields. Materials & …
Ebselen analogs and aurone derivatives and synthesized in good yields. Materials & …
Nickel Catalyzed syn-Selective Aryl Nickelation and Cyclization of Aldehyde/Enone-Tethered Terminal Alkynes with Arylboronic Acids
M Rajesh, MKR Singam, S Puri… - The Journal of …, 2018 - ACS Publications
A syn-arylative nickelation followed by nucleophilic syn-selective cyclization of o-
propargyloxy benzaldehydes is achieved toward the synthesis of chromanol skeletons with …
propargyloxy benzaldehydes is achieved toward the synthesis of chromanol skeletons with …
Enantioselective synthesis of homoisoflavanones by asymmetric transfer hydrogenation and their biological evaluation for antiangiogenic activity
M Heo, B Lee, K Sishtla, X Fei, S Lee… - The Journal of …, 2019 - ACS Publications
Neovascular eye diseases are a major cause of blindness. Excessive angiogenesis is a
feature of several conditions, including wet age-related macular degeneration, proliferative …
feature of several conditions, including wet age-related macular degeneration, proliferative …
Total synthesis of naturally occurring 5, 7, 8-trioxygenated homoisoflavonoids
Homoisoflavonoids are in the subclass of the larger family of flavonoids but have one more
alkyl carbon than flavonoids. Among them, 5, 7, 8-trioxygenated homoisoflavonoids have not …
alkyl carbon than flavonoids. Among them, 5, 7, 8-trioxygenated homoisoflavonoids have not …
Lewis-acid-catalyzed decarboxylative annulation of 2-aminoindole-3-carboxylate with ynals involving [3+ 2] spirocycloaddition and 2, 3-aza migration
2-Aminoindole-3-carboxylates undergo a Lewis-acid-catalyzed decarboxylative annulation
with ynals to afford dihydrochromeno-fused δ-carbolines through a 2, 3-aza migration, via a …
with ynals to afford dihydrochromeno-fused δ-carbolines through a 2, 3-aza migration, via a …
Synthesis and Structure Revision of Naturally Occurring Homoisoflavane (+)-Dracaeconolide B
Dracaeconolide B (1), a naturally occurring homoisoflavane, was isolated from the red resin
of Dracaena cochinchinensis. Efforts have been made to elucidate the exact structure of …
of Dracaena cochinchinensis. Efforts have been made to elucidate the exact structure of …