Fragile X mental retardation protein (FMRP) is the product of the fragile X mental retardation
1 gene (FMR1), a gene that—when epigenetically inactivated by a triplet nucleotide repeat …

The mental retardation protein FMRP is involved in the transport of mRNAs and their
translation at synapses. Patients with fragile X syndrome, in whom FMRP is absent or …

Liquid-liquid phase separation (LLPS) mediates formation of membraneless condensates
such as those associated with RNA processing, but the rules that dictate their assembly …

Fragile X syndrome is the most common form of inherited mental retardation. The disorder is
mainly caused by the expansion of the trinucleotide sequence CGG located in the 5′ UTR …

Fragile X syndrome (FXS) is the most common inherited form of mental retardation and a
leading genetic cause of autism. There is increasing evidence in both FXS and other forms …

Abstract Fragile X Syndrome (FXS) is the most common form of inherited intellectual
disability due to the silencing of the FMR1 gene encoding FMRP (Fragile X Mental …

Fragile X syndrome, as well as other forms of mental retardation and autism, is associated
with altered dendritic spine number and structure. Fragile X syndrome is caused by loss-of …

Fragile X syndrome, a common cause of intellectual disability and autism, is due to
mutational silencing of the FMR1 gene leading to the absence of its gene product, fragile X …

The mental retardation, autistic features, and behavioral abnormalities characteristic of the
Fragile X mental retardation syndrome result from the loss of function of the RNA–binding …

Fragile-X syndrome, the most common monogenic form of mental retardation, is caused by
down-regulation of the expression of Fragile X Mental Retardation Protein (FMRP). FMRP is …