[PDF][PDF] The neurobiology of long COVID

M Monje, A Iwasaki - Neuron, 2022 - cell.com
Persistent neurological and neuropsychiatric symptoms affect a substantial fraction of
people after COVID-19 and represent a major component of the post-acute COVID-19 …

Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis

F Ceban, S Ling, LMW Lui, Y Lee, H Gill… - Brain, behavior, and …, 2022 - Elsevier
Importance COVID-19 is associated with clinically significant symptoms despite resolution of
the acute infection (ie, post-COVID-19 syndrome). Fatigue and cognitive impairment are …

[PDF][PDF] Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation

A Fernández-Castañeda, P Lu, AC Geraghty, E Song… - Cell, 2022 - cell.com
COVID survivors frequently experience lingering neurological symptoms that resemble
cancer-therapy-related cognitive impairment, a syndrome for which white matter microglial …

[HTML][HTML] Understanding COVID-19-associated coagulopathy

EM Conway, N Mackman, RQ Warren… - Nature Reviews …, 2022 - nature.com
Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …

[HTML][HTML] Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment

C Greene, R Connolly, D Brennan, A Laffan… - Nature …, 2024 - nature.com
Vascular disruption has been implicated in coronavirus disease 2019 (COVID-19)
pathogenesis and may predispose to the neurological sequelae associated with long …

Pathophysiology and mechanism of long COVID: a comprehensive review

D Castanares-Zapatero, P Chalon, L Kohn… - Annals of …, 2022 - Taylor & Francis
Background After almost 2 years of fighting against SARS-CoV-2 pandemic, the number of
patients enduring persistent symptoms long after acute infection is a matter of concern. This …

[HTML][HTML] Long COVID or post-acute sequelae of COVID-19 (PASC): an overview of biological factors that may contribute to persistent symptoms

AD Proal, MB VanElzakker - Frontiers in microbiology, 2021 - frontiersin.org
The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused
a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients …

[HTML][HTML] The blood–brain barrier in systemic infection and inflammation

I Galea - Cellular & molecular immunology, 2021 - nature.com
The vascular blood–brain barrier is a highly regulated interface between the blood and
brain. Its primary function is to protect central neurons while signaling the presence of …

Neurovascular injury with complement activation and inflammation in COVID-19

MH Lee, DP Perl, J Steiner, N Pasternack, W Li… - Brain, 2022 - academic.oup.com
The underlying mechanisms by which severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) leads to acute and long-term neurological manifestations remains obscure …

The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2

L Bauer, BM Laksono, FMS de Vrij, SA Kushner… - Trends in …, 2022 - cell.com
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection is associated with
a diverse spectrum of neurological complications during the acute and postacute stages …