[HTML][HTML] ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

PM Thompson, N Jahanshad, CRK Ching… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …

[HTML][HTML] Ethical considerations for precision psychiatry: a roadmap for research and clinical practice

P Fusar-Poli, M Manchia, N Koutsouleris… - European …, 2022 - Elsevier
Precision psychiatry is an emerging field with transformative opportunities for mental health.
However, the use of clinical prediction models carries unprecedented ethical challenges …

SynthSR: A public AI tool to turn heterogeneous clinical brain scans into high-resolution T1-weighted images for 3D morphometry

JE Iglesias, B Billot, Y Balbastre, C Magdamo… - Science …, 2023 - science.org
Every year, millions of brain magnetic resonance imaging (MRI) scans are acquired in
hospitals across the world. These have the potential to revolutionize our understanding of …

Robust machine learning segmentation for large-scale analysis of heterogeneous clinical brain MRI datasets

B Billot, C Magdamo, Y Cheng… - Proceedings of the …, 2023 - National Acad Sciences
Every year, millions of brain MRI scans are acquired in hospitals, which is a figure
considerably larger than the size of any research dataset. Therefore, the ability to analyze …

Quantitative brain morphometry of portable low-field-strength MRI using super-resolution machine learning

JE Iglesias, R Schleicher, S Laguna, B Billot… - Radiology, 2022 - pubs.rsna.org
Background Portable, low-field-strength (0.064-T) MRI has the potential to transform
neuroimaging but is limited by low spatial resolution and low signal-to-noise ratio. Purpose …

[HTML][HTML] Normative modelling of brain morphometry across the lifespan with CentileBrain: algorithm benchmarking and model optimisation

R Ge, Y Yu, YX Qi, Y Fan, S Chen, C Gao… - The Lancet Digital …, 2024 - thelancet.com
The value of normative models in research and clinical practice relies on their robustness
and a systematic comparison of different modelling algorithms and parameters; however …

Greater male than female variability in regional brain structure across the lifespan

LM Wierenga, GE Doucet, D Dima, I Agartz… - Human brain …, 2022 - Wiley Online Library
For many traits, males show greater variability than females, with possible implications for
understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro …

[HTML][HTML] Contextualizing adolescent structural brain development: Environmental determinants and mental health outcomes

L Ferschmann, MGN Bos, MM Herting, KL Mills… - Current opinion in …, 2022 - Elsevier
The spatiotemporal group-level patterns of brain macrostructural development are relatively
well-documented. Current research emphasizes individual variability in brain development …

[HTML][HTML] Four-dimensional mapping of dynamic longitudinal brain subcortical development and early learning functions in infants

L Chen, Y Wang, Z Wu, Y Shan, T Li, SC Hung… - Nature …, 2023 - nature.com
Brain subcortical structures are paramount in many cognitive functions and their aberrations
during infancy are predisposed to various neurodevelopmental and neuropsychiatric …

[HTML][HTML] Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer's disease

M Dyrba, M Hanzig, S Altenstein, S Bader… - Alzheimer's research & …, 2021 - Springer
Background Although convolutional neural networks (CNNs) achieve high diagnostic
accuracy for detecting Alzheimer's disease (AD) dementia based on magnetic resonance …