Materials for the spine: anatomy, problems, and solutions
Disc degeneration affects 12% to 35% of a given population, based on genetics, age,
gender, and other environmental factors, and usually occurs in the lumbar spine due to …
gender, and other environmental factors, and usually occurs in the lumbar spine due to …
Fibrin mechanical properties and their structural origins
RI Litvinov, JW Weisel - Matrix Biology, 2017 - Elsevier
Fibrin is a protein polymer that is essential for hemostasis and thrombosis, wound healing,
and several other biological functions and pathological conditions that involve extracellular …
and several other biological functions and pathological conditions that involve extracellular …
Enzymatically crosslinked silk-hyaluronic acid hydrogels
In this study, silk fibroin and hyaluronic acid (HA) were enzymatically crosslinked to form
biocompatible composite hydrogels with tunable mechanical properties similar to that of …
biocompatible composite hydrogels with tunable mechanical properties similar to that of …
Advanced silk fibroin biomaterials for cartilage regeneration
Silk fibroin is regarded as a natural fibrous protein with tunable mechanical properties,
acceptable biocompatibility, and favorable capability of enhancing attachment, proliferation …
acceptable biocompatibility, and favorable capability of enhancing attachment, proliferation …
Genipin-crosslinked fibrin seeded with oxidized alginate microbeads as a novel composite biomaterial strategy for intervertebral disc cell therapy
CJ Panebianco, S Rao, WW Hom, JH Meyers, TY Lim… - Biomaterials, 2022 - Elsevier
Discectomy procedures alleviate disability caused by intervertebral disc (IVD) herniation, but
do not repair herniation-induced annulus fibrosus (AF) defects. Cell therapy shows promise …
do not repair herniation-induced annulus fibrosus (AF) defects. Cell therapy shows promise …
Silk-based composite scaffolds for tissue engineering applications
S Tandon, B Kandasubramanian… - Industrial & Engineering …, 2020 - ACS Publications
Tissue engineering is an interdisciplinary field that aims toward the repair of the tissues and
organs by bringing together the chemists, material scientists, and biologists to work in …
organs by bringing together the chemists, material scientists, and biologists to work in …
Protein-based materials: from sources to innovative sustainable materials for biomedical applications
Proteins display an essential role in numerous natural systems due to their structural and
biological properties. Given their unique properties, proteins have been thoroughly …
biological properties. Given their unique properties, proteins have been thoroughly …
Current trends in biologics delivery to restore intervertebral disc anabolism
Low back pain is generally attributed to intervertebral disc (IVD) degeneration. This is a
multifactorial disease induced by genetic and environmental factors and that progresses …
multifactorial disease induced by genetic and environmental factors and that progresses …
[HTML][HTML] Advances in biological therapy for nucleus pulposus regeneration
P Priyadarshani, Y Li, L Yao - Osteoarthritis and Cartilage, 2016 - Elsevier
Objective The intervertebral disc (IVD) is composed of the external annulus fibrosus (AF)
and the inner gel-like center, the nucleus pulposus (NP). The elastic NP can function to …
and the inner gel-like center, the nucleus pulposus (NP). The elastic NP can function to …
Processing techniques and applications of silk hydrogels in bioengineering
M Floren, C Migliaresi, A Motta - Journal of functional biomaterials, 2016 - mdpi.com
Hydrogels are an attractive class of tunable material platforms that, combined with their
structural and functional likeness to biological environments, have a diversity of applications …
structural and functional likeness to biological environments, have a diversity of applications …