Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update
Ocular drug delivery is one of the most challenging endeavors among the various available
drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic …
drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic …
Advances in bone marrow stem cell therapy for retinal dysfunction
SS Park, E Moisseiev, G Bauer, JD Anderson… - Progress in retinal and …, 2017 - Elsevier
The most common cause of untreatable vision loss is dysfunction of the retina. Conditions,
such as age-related macular degeneration, diabetic retinopathy and glaucoma remain …
such as age-related macular degeneration, diabetic retinopathy and glaucoma remain …
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration
CL Deng, CB Hu, ST Ling, N Zhao, LH Bao… - Cell Death & …, 2021 - nature.com
Photoreceptor apoptosis is recognized as one key pathogenesis of retinal degeneration, the
counteraction of which represents a promising approach to safeguard visual function …
counteraction of which represents a promising approach to safeguard visual function …
Restoring light sensitivity using tunable near-infrared sensors
D Nelidova, RK Morikawa, CS Cowan, Z Raics… - Science, 2020 - science.org
Enabling near-infrared light sensitivity in a blind human retina may supplement or restore
visual function in patients with regional retinal degeneration. We induced near-infrared light …
visual function in patients with regional retinal degeneration. We induced near-infrared light …
Gold nanoparticles in ophthalmology
F Masse, M Ouellette, G Lamoureux… - Medicinal research …, 2019 - Wiley Online Library
Many research projects are underway to improve the diagnosis and therapy in
ophthalmology. Indeed, visual acuity deficits affect 285 million people worldwide and …
ophthalmology. Indeed, visual acuity deficits affect 285 million people worldwide and …
Cellular reparative mechanisms of mesenchymal stem cells for retinal diseases
The use of multipotent mesenchymal stem cells (MSCs) has been reported as promising for
the treatment of numerous degenerative disorders including the eye. In retinal degenerative …
the treatment of numerous degenerative disorders including the eye. In retinal degenerative …
Management of retinitis pigmentosa by Wharton's jelly derived mesenchymal stem cells: preliminary clinical results
E Özmert, U Arslan - Stem cell research & therapy, 2020 - Springer
Purpose The aim of this study is to determine if umbilical cord Wharton's jelly derived
mesenchymal stem cells implanted in sub-tenon space have beneficial effects on visual …
mesenchymal stem cells implanted in sub-tenon space have beneficial effects on visual …
Management of retinitis pigmentosa by Wharton's jelly-derived mesenchymal stem cells: prospective analysis of 1-year results
E Özmert, U Arslan - Stem cell research & therapy, 2020 - Springer
Purpose The aim of the study was to investigate annual structural and functional results, and
their correlation with inheritance pattern of retinitis pigmentosa (RP) patients who were …
their correlation with inheritance pattern of retinitis pigmentosa (RP) patients who were …
Human Wharton's jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors
JE Millán-Rivero, FM Nadal-Nicolás… - Scientific Reports, 2018 - nature.com
Mesenchymal stem cell (MSC) transplantation is emerging as an ideal tool to restore the
wounded central nervous system (CNS). MSCs isolated from extra-embryonic tissues have …
wounded central nervous system (CNS). MSCs isolated from extra-embryonic tissues have …
Human primitive mesenchymal stem cell-derived retinal progenitor cells improved neuroprotection, neurogenesis, and vision in rd12 mouse model of retinitis …
C Brown, P Agosta, C McKee, K Walker… - Stem Cell Research & …, 2022 - Springer
Background Currently, there is no treatment for retinal degenerative diseases (RDD) such as
retinitis pigmentosa (RP). Stem cell-based therapies could provide promising opportunities …
retinitis pigmentosa (RP). Stem cell-based therapies could provide promising opportunities …