[HTML][HTML] Antidepressant effects of coumarins and their derivatives: A critical analysis of research advances

NA Akwu, M Lekhooa, D Deqiang, AO Aremu - European Journal of …, 2023 - Elsevier
Coumarins and their derivatives are non-flavonoids polyphenols with diverse
pharmacological activities including anti-depressant effects. This study systematically …

[HTML][HTML] Pharmacological activities of esculin and esculetin: A review

T Cai, B Cai - Medicine, 2023 - journals.lww.com
Esculin and esculetin are 2 widely studied coumarin components of Cortex Fraxini, which is
a well-known herbal medicine with a 2000-year history. In vivo and in vitro studies have …

3-Substituted Coumarins Inhibit NorA and MepA Efflux Pumps of Staphylococcus aureus

JB Araújo-Neto, CDM Oliveira-Tintino, GA de Araújo… - Antibiotics, 2023 - mdpi.com
Coumarins are compounds with scientifically proven antibacterial properties, and
modifications to the chemical structure are known to improve their effects. This information is …

[HTML][HTML] Coumarin: A natural solution for alleviating inflammatory disorders

F Saadati, AM Chahardehi, N Jamshidi… - Current Research in …, 2024 - Elsevier
Coumarin, a naturally occurring compound found in various plants, has a rich history of use
in traditional medicine. Recent research has highlighted its anti-inflammatory properties …

Cytogenotoxicity assessment of 3‐(3, 4‐dihydroxyphenyl)‐7, 8‐dihydroxycoumarin on HepG2/C3A cells and leukocytes

APM Castanha, LM Almeida‐Terassi… - Journal of Applied …, 2023 - Wiley Online Library
Abstract 3‐(3, 4‐Dihydroxyphenyl)‐7, 8‐dihydroxycoumarin is a newly synthesized
coumarin derivative with a potent antioxidant effect. The aim of the present study is to …

[HTML][HTML] Synthesis, characterization, and biological evaluation of coumarin-nitric oxide donor hybrids as anti-tubercular agents

AI Kareem, SF Malan, E Kapp, S Shamido… - European Journal of …, 2024 - Elsevier
This study presents a series of coumarin nitric oxide donor hybrids that were synthesized,
and characterized using FT-IR, H NMR, C NMR, and HR-MS techniques. Initial screening for …

Acetylcholine Inhibitory Study of Novel Thio Linked Coumarin-Benzimidazole Derivatives: Design, Synthesis, Computational, and In Silico Molecular Docking Studies

THM Nayaka, I Pushpavathi, Pavithra… - Russian Journal of …, 2024 - Springer
Objective: This article focused on the synthesis and characterization of heterocyclic
compounds containing two heteroatoms, as well as computational investigations, the …

[HTML][HTML] The quality control and hypoglycemic effect of Cinnamomi Cortex aqueous extract

X Hao, Z Jin, R Gao, S Li, C Li, L Liu, J Wang - Journal of Future Foods, 2024 - Elsevier
Cinnamomi Cortex was a material as medicinal and edible resources and it has been
demonstrated that Cinnamomi Cortex aqueous extract (CCAE) possess hypoglycemic effect …

Analytical methods for furanochromone natural product, khellin and its inspired drug candidates, amiodarone and sodium cromoglycate

RP Shah, SS Bharate - Critical Reviews in Analytical Chemistry, 2024 - Taylor & Francis
Khellin is the key furanocoumarin of Ammi visnaga L.(Lam.) that exhibits various biological
properties. This unique natural product has inspired the discovery of two first-in-class drugs …

Examining the Antioxidant and Superoxide Radical Scavenging Activity of Anise, (Pimpinella anisum L. Seeds), Esculetin, and 4-Methyl-Esculetin Using X-ray …

M Rossi, F Caruso, N Thieke, S Belli, A Kim… - Pharmaceuticals, 2023 - mdpi.com
Pimpinella anisum L., or anise, is a plant that, besides its nutritional value, has been used in
traditional medical practices and described in many cultures in the Mediterranean region. A …