Radiotherapy-induced digestive injury: diagnosis, treatment and mechanisms

G Chen, Y Han, H Zhang, W Tu, S Zhang - Frontiers in oncology, 2021 - frontiersin.org
Radiotherapy is one of the main therapeutic methods for treating cancer. The digestive
system consists of the gastrointestinal tract and the accessory organs of digestion (the …

Predicting toxicity in radiotherapy for prostate cancer

V Landoni, C Fiorino, C Cozzarini, G Sanguineti… - Physica Medica, 2016 - Elsevier
This comprehensive review addresses most organs at risk involved in planning optimization
for prostate cancer. It can be considered an update of a previous educational review that …

Bowel morbidity following radiochemotherapy and image-guided adaptive brachytherapy for cervical cancer: physician-and patient reported outcome from the …

NBK Jensen, R Pötter, K Kirchheiner, L Fokdal… - Radiotherapy and …, 2018 - Elsevier
Abstract Background/Purpose This study describes late bowel morbidity prospectively
assessed in the multi-institutional EMBRACE study on MRI-guided adaptive brachytherapy …

A systematic post-QUANTEC review of tolerance doses for late toxicity after prostate cancer radiation therapy

CE Olsson, A Jackson, JO Deasy, M Thor - International Journal of …, 2018 - Elsevier
Purpose The aims of this study were to systematically review tolerance doses for late distinct
gastrointestinal (GI), genitourinary (GU), and sexual dysfunction (SD) symptoms after …

A systematic review of dose-volume predictors and constraints for late bowel toxicity following pelvic radiotherapy

R Jadon, E Higgins, L Hanna, M Evans, B Coles… - Radiation …, 2019 - Springer
Background Advanced pelvic radiotherapy techniques aim to reduce late bowel toxicity
which can severely impact the lives of pelvic cancer survivors. Although advanced …

Severity and persistency of late gastrointestinal morbidity in locally advanced cervical cancer: lessons learned from EMBRACE-I and implications for the future

S Spampinato, NBK Jensen, R Pötter, LU Fokdal… - International Journal of …, 2022 - Elsevier
Purpose The purpose was to evaluate patient-and treatment-related risk factors for physician-
assessed and patient-reported gastrointestinal (GI) symptoms after radio (chemo) therapy …

[HTML][HTML] Estimates of alpha/beta (α/β) ratios for individual late rectal toxicity endpoints: an analysis of the CHHiP trial

DH Brand, SC Brüningk, A Wilkins, K Fernandez… - International Journal of …, 2021 - Elsevier
Purpose Changes in fraction size of external beam radiation therapy exert nonlinear effects
on subsequent toxicity. Commonly described by the linear-quadratic model, fraction size …

Spatial rectal dose/volume metrics predict patient-reported gastro-intestinal symptoms after radiotherapy for prostate cancer

O Casares-Magaz, LP Muren, V Moiseenko… - Acta …, 2017 - Taylor & Francis
Abstract Background: Gastro-intestinal (GI) toxicity after radiotherapy (RT) for prostate
cancer reduces patient's quality of life. In this study, we explored associations between …

Urinary bladder dose–response relationships for patient-reported genitourinary morbidity domains following prostate cancer radiotherapy

M Thor, C Olsson, JH Oh, SE Petersen… - Radiotherapy and …, 2016 - Elsevier
Background and purpose Radiotherapy (RT) induced genitourinary (GU) morbidity is
typically assessed by physicians as single symptoms or aggregated scores including …

Patient-reported intestinal toxicity from whole pelvis intensity-modulated radiotherapy: first quantification of bowel dose–volume effects

C Sini, BN Chiorda, P Gabriele, G Sanguineti… - Radiotherapy and …, 2017 - Elsevier
Background and purpose Intestinal toxicity is commonly experienced during whole-pelvis
intensity-modulated radiotherapy (WPRT) for prostate cancer. The aim of the current study …