Pulmonary surfactant is a lipid/protein complex synthesized by the alveolar epithelium and
secreted into the airspaces, where it coats and protects the large respiratory air–liquid …

Different families of endogenous lectins use complementary defense strategies against
pathogens. They may recognize non-self glycans typically found on pathogens and/or host …

Soluble defense collagens form a group of secreted proteins that are primarily involved in
host defense. All defense collagens contain a globular recognition domain contiguous to a …

The purpose of the current study was to examine the binding of pulmonary surfactant protein
A (SP-A) to TLR4 and MD-2, which are critical signaling receptors for lipopolysaccharides …

CD6 is a lymphocyte receptor that belongs to the scavenger receptor cysteine-rich
superfamily. Because some members of the scavenger receptor cysteine-rich superfamily …

The major role of chemokines is to act as a chemoattractant to guide the migration of
immune cells to the infectious sites. In the current study, we found that CiCXCL20a, a teleost …

The exploration of therapies combining antimicrobial lung proteins and conventional
antibiotics is important due to the growing problem of multidrug-resistant bacteria. The aim of …

Antimicrobial peptides (AMPs) are important potential alternatives to conventional therapies
against bacterial infections. rBPI21 is a 21 kDa peptide based on the N-terminal region of …

Lung surfactant protein A (SP-A) plays an important function in modulating inflammation in
the lung. However, the exact role of SP-A and the mechanism by which SP-A affects IFN-γ …

The innate immune systems of humans and other animals are activated by
lipopolysaccharides (LPS), which are glucosamine-based phospholipids that form the outer …