Cellular human tissue-engineered skin substitutes investigated for deep and difficult to heal injuries

Á Sierra-Sánchez, KH Kim, G Blasco-Morente… - NPJ Regenerative …, 2021 - nature.com
Wound healing is an important function of skin; however, after significant skin injury (burns)
or in certain dermatological pathologies (chronic wounds), this important process can be …

An overview of recent developments in the management of burn injuries

E Radzikowska-Büchner, I Łopuszyńska… - International journal of …, 2023 - mdpi.com
According to the World Health Organization (WHO), around 11 million people suffer from
burns every year, and 180,000 die from them. A burn is a condition in which heat, chemical …

3D bioprinting of integral ADSCs-NO hydrogel scaffolds to promote severe burn wound healing

Y Wu, T Liang, Y Hu, S Jiang, Y Luo… - Regenerative …, 2021 - academic.oup.com
Severe burns are challenging to heal and result in significant death throughout the world.
Adipose-derived mesenchymal stem cells (ADSCs) have emerged as a promising treatment …

Advancements in cell-based therapies for thermal burn wounds: a comprehensive systematic review of clinical trials outcomes

Y Yassaghi, Y Nazerian, F Niazi, H Niknejad - Stem cell research & …, 2024 - Springer
Background Burn trauma is one of the major causes of morbidity and mortality worldwide.
The standard management of burn wounds consists of early debridement, dressing …

Application of adipose-tissue derived products for burn wound healing

H Malekzadeh, Z Tirmizi, JA Arellano, FM Egro, A Ejaz - Pharmaceuticals, 2023 - mdpi.com
Burn injuries are a significant global health concern, leading to high morbidity and mortality.
Deep burn injuries often result in delayed healing and scar formation, necessitating effective …

Systematic review of stem-cell-based therapy of burn wounds: lessons learned from animal and clinical studies

JL Henriksen, NB Sørensen, T Fink, V Zachar… - Cells, 2020 - mdpi.com
Treatment of severe burn wounds presents a daunting medical challenge, and novel
approaches promoting healing and reducing scarring are highly desirable. The application …

Orchestration of mesenchymal stem/stromal cells and inflammation during wound healing

M Zhu, L Cao, S Melino, E Candi… - Stem Cells …, 2023 - academic.oup.com
Wound healing is a complex process and encompasses a number of overlapping phases,
during which coordinated inflammatory responses following tissue injury play dominant …

Unveiling advanced strategies for therapeutic stem cell interventions in severe burn injuries: a comprehensive review

P Das, D Pal, S Roy, S Chaudhuri… - … Journal of Surgery, 2024 - journals.lww.com
This comprehensive review explores the complex terrain of stem cell therapies as a potential
therapeutic frontier in the healing of complicated burn wounds. Serious tissue damage …

[HTML][HTML] An ADSC-loaded dermal regeneration template promotes full-thickness wound healing

J Xu, X Chen, J Wang, B Zhang, W Ge, J Wang… - Regenerative …, 2024 - Elsevier
Introduction Full-thickness wounds lead to delayed wound healing and scarring. Adipose-
derived stem cell (ADSC) grafting promotes wound healing and minimizes scarring, but the …

Design, development, analysis and comparison of human tissue-engineered skin substitute models

Á Sierra Sánchez - 2024 - digibug.ugr.es
Tissue engineering is a multidisciplinary field which involves several areas such as cell
biology, material science, engineering, or medicine. It appears as a necessity to solve the …