Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Similarities in neocortical circuit organization across areas and species suggest a common
strategy to process diverse types of information, including sensation from diverse modalities …

The influence of motor activity on sensory processing is crucial for perception and motor
execution. However, the underlying circuits are not known. To unravel the circuit by which …

Emerging evidence indicates impairments in somatosensory function may be a major
contributor to motor dysfunction associated with neurologic injury or disorders. However, the …

Understanding cortical circuits will require mapping the connections between specific
populations of neurons, as well as determining the dendritic locations where the synapses …

In the rodent vibrissal system, active sensation and sensorimotor integration are mediated in
part by connections between barrel cortex and vibrissal motor cortex. Little is known about …

Satb2 is a DNA-binding protein that regulates chromatin organization and gene expression.
In the developing brain, Satb2 is expressed in cortical neurons that extend axons across the …

Callosal projection neurons (CPN) are a diverse population of neocortical projection
neurons that connect the two hemispheres of the cerebral cortex via the corpus callosum …

In the visual system of primates, different neuronal pathways are specialized for processing
information about the spatial coordinates of objects and their identity—that …

Neocortical areas are believed to be organized into vertical modules, the cortical columns,
and the horizontal layers 1–6. In the somatosensory barrel cortex these columns are defined …