[HTML][HTML] Diverse roles of mitochondria in ischemic stroke

JL Yang, S Mukda, SD Chen - Redox biology, 2018 - Elsevier
Stroke is the leading cause of adult disability and mortality in most developing and
developed countries. The current best practices for patients with acute ischemic stroke …

Thiazolidinediones as antidiabetic agents: A critical review

MJ Nanjan, M Mohammed, BRP Kumar… - Bioorganic …, 2018 - Elsevier
Abstract Thiazolidinediones (TZDs) or Glitazones are an important class of insulin
sensitizers used in the treatment of Type 2 diabetes mellitus (T2DM). TZDs were reported for …

The role of mitochondria in liver ischemia‐reperfusion injury: from aspects of mitochondrial oxidative stress, mitochondrial fission, mitochondrial membrane permeable …

H Zhang, Q Yan, X Wang, X Chen… - Oxidative medicine …, 2021 - Wiley Online Library
Ischemia‐reperfusion injury (IRI) has indeed been shown as a main complication of
hepatectomy, liver transplantation, trauma, and hypovolemic shock. A large number of …

A review of pterostilbene antioxidant activity and disease modification

D McCormack, D McFadden - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Pterostilbene (trans‐3, 5‐dimethoxy‐4‐hydroxystilbene) is a natural dietary compound and
the primary antioxidant component of blueberries. It has increased bioavailability in …

Roles of oxidative stress, apoptosis, PGC-1α and mitochondrial biogenesis in cerebral ischemia

SD Chen, DI Yang, TK Lin, FZ Shaw, CW Liou… - International journal of …, 2011 - mdpi.com
The primary physiological function of mitochondria is to generate adenosine triphosphate
through oxidative phosphorylation via the electron transport chain. Overproduction of …

Paeoniflorin protects against ischemia-induced brain damages in rats via inhibiting MAPKs/NF-κB-mediated inflammatory responses

RB Guo, GF Wang, AP Zhao, J Gu, XL Sun, G Hu - PLoS One, 2012 - journals.plos.org
Paeoniflorin (PF), the principal component of Paeoniae Radix prescribed in traditional
Chinese medicine, has been reported to exhibit many pharmacological effects including …

Genomic and non-genomic actions of glucocorticoids on adipose tissue lipid metabolism

N Mir, SA Chin, MC Riddell, JL Beaudry - International Journal of …, 2021 - mdpi.com
Glucocorticoids (GCs) are hormones that aid the body under stress by regulating glucose
and free fatty acids. GCs maintain energy homeostasis in multiple tissues, including those in …

Emerging targets for modulation of immune response and inflammation in stroke

K Thapa, K Shivam, H Khan, A Kaur, K Dua… - Neurochemical …, 2023 - Springer
The inflammatory and immunological responses play a significant role after stroke. The
innate immune activation stimulated by microglia during stroke results in the migration of …

Peroxisome proliferator-activated receptor gamma (PPAR-γ) and neurodegenerative disorders

YC Chen, JS Wu, HD Tsai, CY Huang, JJ Chen… - Molecular …, 2012 - Springer
As the growth of the aging population continues to accelerate globally, increased
prevalence of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's …

14-3-3 proteins in neurodegeneration

P Steinacker, A Aitken, M Otto - Seminars in cell & developmental biology, 2011 - Elsevier
Among the first reported functions of 14-3-3 proteins was the regulation of tyrosine
hydroxylase (TH) activity suggesting a possible involvement of 14-3-3 proteins in …