Hyperammonaemia (HA) as a consequence of numerous primary or secondary causes,
gives rise to clinical manifestations due to its toxic effects on the brain. The neurological …

Ammonia is one of the main players in the pathogenesis of hepatic encephalopathy (HE) in
patients with chronic liver diseases. The usefulness of measuring ammonemia has been …

Chitosan films have attracted increased attention in the field of sensors because of
chitosan's unique chemico-physical properties, including high adsorption capacity, filmability …

The liver is the second largest single organ in the horse (skin is first), accounting for
approximately 1.5% of body weight. 1 In the adult horse, the liver is positioned obliquely in …

Ammonia physiology is important to numerous disease states including urea cycle disorders
and hepatic encephalopathy. However, many unknowns persist regarding the ammonia …

Lysinuric protein intolerance (LPI) is a rare inborn error of metabolism (IEM), classified as an
inherited aminoaciduria, caused by mutations in the SLC7A7 gene, leading to a defective …

Adult onset urea cycle disorders (UCD) may present with psychiatric symptoms, occasionally
as the initial presentation. We aimed to describe the characteristics of patients presenting …

Liver fibrosis staging is a key element driving the prognosis of patients with chronic liver
disease. Currently, biopsy is the only technique capable of diagnosing liver fibrosis in …

Background: Hyperammonemia is neurotoxic and as such can be a medical emergency.
Preanalytical factors greatly influence the blood ammonia concentration results. Aims and …

Blood ammonia is routinely used in clinical settings to assess systemic ammonia in hepatic
encephalopathy and urea cycle disorders. Despite its drawbacks, blood measurement is …