Discovery of essential kinetoplastid-insect adhesion proteins and their function in Leishmania-sand fly interactions

R Yanase, K Pruzinova, BO Owino, E Rea… - Nature …, 2024 - nature.com
Leishmania species, members of the kinetoplastid parasites, cause leishmaniasis, a
neglected tropical disease, in millions of people worldwide. Leishmania has a complex life …

Interaction of Trypanosoma cruzi, Triatomines and the Microbiota of the Vectors—A Review

GA Schaub - Microorganisms, 2024 - mdpi.com
This review summarizes the interactions between Trypanosoma cruzi, the etiologic agent of
Chagas disease, its vectors, triatomines, and the diverse intestinal microbiota of triatomines …

Adhesion of Crithidia fasciculata promotes a rapid change in developmental fate driven by cAMP signaling

S Denecke, MF Malfara, KR Hodges, NA Holmes… - Msphere, 2024 - journals.asm.org
Trypanosomatids are single-celled parasites responsible for human and animal disease.
Typically, colonization of an insect host is required for transmission. Stable attachment of …

Genetic modification of the bee parasite Crithidia bombi for improved visualization and protein localization

BV Bieber, SG Lockett, SK Glasser, FAS Clair… - Experimental …, 2024 - Elsevier
Crithidia bombi is a trypanosomatid parasite that infects several species of bumble bees
(Bombus spp.), by adhering to their intestinal tract. Crithidia bombi infection impairs learning …

TcCARP3 modulates compartmentalized cAMP signals involved in osmoregulation, infection of mammalian cells, and colonization of the triatomine vector in the …

J Carlson, M Ahmed, R Hunter, SF Hoque, JB Benoit… - bioRxiv, 2024 - biorxiv.org
Trypanosoma cruzi is the causative agent of Chagas disease, a zoonotic infectious disease
considered a leading cause of cardiomyopathy, disability, and premature death in the …

Reducing Infection Once and Floral: Examining the Effects of Sunflower Pollen on In Vitro Growth and Attachment of Crithidia bombi, a Parasite of Bumblebees

FAS Clair - 2024 - search.proquest.com
Crithidia bombi is a parasite of bumblebees that reduces the fitness and reproductive
capacity of its host. Like most monoxenous trypanosomatids, C. bombi colonize their insect …