Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

This review on acne transcriptomics allows for deeper insights into the pathogenesis of acne
and isotretinoin's mode of action. Puberty-induced insulin-like growth factor 1 (IGF-1), insulin …

Despite the key roles of perilipin-2 (PLIN2) in governing lipid droplet (LD) metabolism, the
mechanisms that regulate PLIN2 levels remain incompletely understood. Here, we leverage …

Organelle interactions play a significant role in compartmentalizing metabolism and
signaling. Lipid droplets (LDs) interact with numerous organelles, including mitochondria …

Perilipins are abundant lipid droplet (LD) proteins present in all metazoans and also in
Amoebozoa and fungi. Humans express five perilipins, which share a similar domain …

Conclusions: The macrophage STING-YAP axis controls hepatic steatosis by
reprogramming lipid metabolism in a transmembrane protein 205/mitofusin 2/protein …

Excessive storage of lipid droplets (LDs) in skeletal muscles is a hallmark of type 2 diabetes.
However, LD morphology displays a high degree of subcellular heterogeneity and varies …

Lipids are a big family of molecules with a vast number of functions in the cell membranes,
within the cytoplasm, and extracellularly. Lipid droplets (LDs) are the most common storage …

Simple Summary This review highlights the importance of perilipins in lipid metabolism and
their potential as therapeutic targets for lipid-associated diseases like cancer and obesity …

Fatty liver is characterized by the expansion of lipid droplets (LDs) and is associated with the
development of many metabolic diseases. We assessed the morphology of hepatic LDs and …