Mass spectrometry (MS) is becoming increasingly popular in the field of structural biology for
analyzing protein three‐dimensional‐structures and for mapping protein–protein …

The chaperonin containing TCP-1 (CCT) is required for the production of native actin and
tubulin and numerous other proteins, several of which are involved in cell cycle progression …

Parkinson's disease is caused by a progressive loss of the midbrain dopamine (DA) neurons
in the substantia nigra pars compacta. Although the main cause of Parkinson's disease …

The cytoskeletal proteins tubulin and actin are the obligate substrates of TCP-1 ring
complex/Chaperonin containing TCP-1 (TRiC/CCT), and their folding involves co …

The eukaryotic cytosolic chaperonin containing TCP‐1 (CCT) has an important function in
maintaining cellular homoeostasis by assisting the folding of many proteins, including the …

Actins and tubulins are abundant cytoskeletal proteins that support diverse cellular
processes. Owing to the unique properties of these filament-forming proteins, an intricate …

The cytosolic chaperonin CCT (chaperonin containing TCP-1) is an ATP-dependent double-
ring protein machine mediating the folding of members of the eukaryotic cytoskeletal protein …

The cytosolic chaperonin CCT is indispensable to eukaryotic life, folding the cytoskeletal
proteins actin and tubulin along with an estimated 10% of the remaining proteome …

Members of the phosducin gene family were initially proposed to act as down-regulators of
G protein signaling by binding G protein βγ dimers (Gβγ) and inhibiting their ability to interact …

The cytosolic chaperonin CCT is a 1‐MDa protein‐folding machine essential for eukaryotic
life. The CCT interactome shows involvement in folding and assembly of a small range of …