DNA-binding mechanism and evolution of replication protein A

C Madru, M Martínez-Carranza, S Laurent… - Nature …, 2023 - nature.com
Abstract Replication Protein A (RPA) is a heterotrimeric single stranded DNA-binding protein
with essential roles in DNA replication, recombination and repair. Little is known about the …

Aptamers: ushering in new hopes in targeted glioblastoma therapy

D Chatterjee, S Bhattacharya, L Kumari… - Journal of Drug …, 2024 - Taylor & Francis
Glioblastoma, a formidable brain cancer, has remained a therapeutic challenge due to its
aggressive nature and resistance to conventional treatments. Recent data indicate that …

The Impact of Single-Stranded DNA-Binding Protein SSB and Putative SSB-Interacting Proteins on Genome Integrity in the Thermophilic Crenarchaeon Sulfolobus …

S Suzuki, N Kurosawa - International journal of molecular sciences, 2023 - mdpi.com
The study of DNA repair in hyperthermophiles has the potential to elucidate the mechanisms
of genome integrity maintenance systems under extreme conditions. Previous biochemical …

[HTML][HTML] Isolation and Characterization of a Novel Phage against Vibrio alginolyticus Belonging to a New Genus

J Gao, Y Zhu, R Zhang, J Xu, R Zhou, M Di… - International Journal of …, 2024 - mdpi.com
Vibrio alginolyticus causes substantial economic losses in the aquaculture industry. With the
rise of multidrug-resistant Vibrio strains, phages present a promising solution. Here, a novel …

PrgE: an OB-fold protein from plasmid pCF10 with striking differences to prototypical bacterial SSBs

A Breidenstein, A Lamy, CPJ Bader… - Life Science …, 2024 - life-science-alliance.org
A major pathway for horizontal gene transfer is the transmission of DNA from donor to
recipient cells via plasmid-encoded type IV secretion systems (T4SSs). Many conjugative …