Classification of radiation effects for dose limitation purposes: history, current situation and future prospects

N Hamada, Y Fujimichi - Journal of radiation research, 2014 - academic.oup.com
Radiation exposure causes cancer and non-cancer health effects, each of which differs
greatly in the shape of the dose–response curve, latency, persistency, recurrence, curability …

Targeting the thioredoxin system as a strategy for cancer therapy: Miniperspective

M Bian, R Fan, S Zhao, W Liu - Journal of medicinal chemistry, 2019 - ACS Publications
Thioredoxin reductase (TrxR) participates in the regulation of redox reactions in organisms.
It works mainly via its substrate molecule, thioredoxin, to maintain the redox balance and …

Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research

EA Ainsbury, S Barnard, S Bright, C Dalke… - … Research/Reviews in …, 2016 - Elsevier
The lens of the eye has long been considered as a radiosensitive tissue, but recent research
has suggested that the radiosensitivity is even greater than previously thought. The 2012 …

Redox-dependent catalase mimetic cerium oxide-based nanozyme protect human hepatic cells from 3-AT induced acatalasemia

R Singh, S Singh - Colloids and Surfaces B: Biointerfaces, 2019 - Elsevier
Recently, CeNPs have emerged as an effective therapeutic agent due to their redox-active
nature encompassing the ability to switch between+ 4 or+ 3 oxidation states of surface “Ce” …

Etiology of posterior subcapsular cataracts based on a review of risk factors including aging, diabetes, and ionizing radiation

RB Richardson, EA Ainsbury, CR Prescott… - International journal of …, 2020 - Taylor & Francis
Purpose Since the exact development of posterior subcapsular cataracts (PSCs) is poorly
understood, we review various risk factors and propose a two-stage etiology for PSCs …

Application of metal-based nanozymes in inflammatory disease: a review

R Li, X Hou, L Li, J Guo, W Jiang… - … in Bioengineering and …, 2022 - frontiersin.org
Reactive oxygen species (ROS) are metabolites of normal cells in organisms, and normal
levels of ROS in cells are essential for maintaining cell signaling and other intracellular …

Noncancer effects of ionizing radiation exposure on the eye, the circulatory system and beyond: Developments made since the 2011 ICRP Statement on Tissue …

N Hamada - Radiation Research, 2023 - meridian.allenpress.com
For radiation protection purposes, noncancer effects with a threshold-type dose-response
relationship have been classified as tissue reactions (formerly called nonstochastic or …

An update on effects of ionizing radiation exposure on the eye

N Hamada, TV Azizova, MP Little - The British journal of …, 2020 - academic.oup.com
The International Commission on Radiological Protection (ICRP) has considered for over 60
years that the lens of the eye is among the most radiosensitive tissues, and has …

[HTML][HTML] Cataractogenic load–a concept to study the contribution of ionizing radiation to accelerated aging in the eye lens

A Uwineza, AA Kalligeraki, N Hamada, M Jarrin… - … Research/Reviews in …, 2019 - Elsevier
Ionizing radiation (IR) damages DNA and other macromolecules, including proteins and
lipids. Most cell types can repair DNA damage and cycle continuously their macromolecules …

Guidance on radiation dose limits for the lens of the eye: overview of the recommendations in NCRP Commentary No. 26

LT Dauer, EA Ainsbury, J Dynlacht, D Hoel… - … journal of radiation …, 2017 - Taylor & Francis
Purpose: This review summarizes the conclusions and recommendations of the new
National Council on Radiation Protection and Measurements (NCRP) Commentary No. 26 …