[HTML][HTML] Melatonin synthesis and function: evolutionary history in animals and plants

D Zhao, Y Yu, Z Zhao, R Sharma… - Frontiers in …, 2019 - frontiersin.org
Melatonin is an ancient molecule that can be traced back to the origin of life. Melatonin's
initial function was likely that as a free radical scavenger. Melatonin presumably evolved in …

[HTML][HTML] Melatonin and phytomelatonin: Chemistry, biosynthesis, metabolism, distribution and bioactivity in plants and animals—An overview

G Mannino, C Pernici, G Serio, C Gentile… - International Journal of …, 2021 - mdpi.com
Melatonin is a ubiquitous indolamine, largely investigated for its key role in the regulation of
several physiological processes in both animals and plants. In the last century, it was …

Melatonin as a hormone: new physiological and clinical insights

J Cipolla-Neto, FG Amaral - Endocrine reviews, 2018 - academic.oup.com
Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Melatonin in type 2 diabetes mellitus and obesity

A Karamitri, R Jockers - Nature Reviews Endocrinology, 2019 - nature.com
Despite considerable advances in the past few years, obesity and type 2 diabetes mellitus
(T2DM) remain two major challenges for public health systems globally. In the past 9 years …

[HTML][HTML] Exogenous melatonin promotes seed germination and osmotic regulation under salt stress in cotton (Gossypium hirsutum L.)

L Chen, L Liu, B Lu, T Ma, D Jiang, J Li, K Zhang… - Plos one, 2020 - journals.plos.org
Melatonin (MT; N-acetyI-5-methoxytryptamine) is an amine hormone involved in abiotic
stress resistance. Previous studies have confirmed that melatonin can promote seed …

Chronotherapy

DP Cardinali, GM Brown, SR Pandi-Perumal - Handbook of Clinical …, 2021 - Elsevier
The objective of chronotherapy is to optimize medical treatments taking into account the
body's circadian rhythms. Chronotherapy is referred to and practiced in two different …

Melatonin alleviates the toxic effect of di (2-ethylhexyl) phthalate on oocyte quality resulting from CEBPB suppression during primordial follicle formation

JJ Wang, XY Zhang, Y Zeng, QC Liu, XL Feng… - Journal of Hazardous …, 2024 - Elsevier
Presently, the exposure of plasticizers to humans and animals occurs daily, which pose a
potential threat to reproductive health. In the present study, a pregnant mouse model …

[HTML][HTML] Sleep disorders in Alzheimer's disease: the predictive roles and potential mechanisms

H Kuang, YG Zhu, ZF Zhou, MW Yang… - Neural Regeneration …, 2021 - journals.lww.com
Sleep disorders are common in patients with Alzheimer's disease, and can even occur in
patients with amnestic mild cognitive impairment, which appears before Alzheimer's …

Efficacy of melatonin in non-intensive care unit patients with COVID-19 pneumonia and sleep dysregulation

LI Brusco, P Cruz, A Cangas, C González Rojas… - 2021 - ri.conicet.gov.ar
The association of sleep disruption with a higher vulnerability to COVID-19 infection is
asubject of major clinical importance. In patients with pneumonia associated with COVID …

A new perspective of melatonin in stress tolerance through regulation of nutrients

T Seth, S Asija, S Khatoon, N Iqbal, S Umar… - South African Journal of …, 2023 - Elsevier
Plants are subjected to constant environmental changes, which lead to deleterious mineral
deficiencies resulting in constraints in plant growth, and thereby limiting productivity …