From ecotoxicology to nanoecotoxicology

A Kahru, HC Dubourguier - Toxicology, 2010 - Elsevier
For hazard assessment of NPs quantitative nanoecotoxicological data are required. The
objective of this review was to evaluate the currently existing literature data on toxicity (L (E) …

Evolving scenario of big data and Artificial Intelligence (AI) in drug discovery

MK Tripathi, A Nath, TP Singh, AS Ethayathulla… - Molecular Diversity, 2021 - Springer
The accumulation of massive data in the plethora of Cheminformatics databases has made
the role of big data and artificial intelligence (AI) indispensable in drug design. This has …

The comparative toxicogenomics database: update 2019

AP Davis, CJ Grondin, RJ Johnson… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) is a premier
public resource for literature-based, manually curated associations between chemicals …

The Comparative Toxicogenomics Database's 10th year anniversary: update 2015

AP Davis, CJ Grondin, K Lennon-Hopkins… - Nucleic acids …, 2015 - academic.oup.com
Ten years ago, the Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) was
developed out of a need to formalize, harmonize and centralize the information on …

The comparative toxicogenomics database: update 2013

AP Davis, CG Murphy, R Johnson, JM Lay… - Nucleic acids …, 2013 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) provides
information about interactions between environmental chemicals and gene products and …

Xenobiotic metabolism and transport in Caenorhabditis elegans

JH Hartman, SJ Widmayer… - Journal of Toxicology …, 2021 - Taylor & Francis
Caenorhabditis elegans has emerged as a major model in biomedical and environmental
toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been …

A review on the recent applications of deep learning in predictive drug toxicological studies

K Sinha, N Ghosh, PC Sil - Chemical Research in Toxicology, 2023 - ACS Publications
Drug toxicity prediction is an important step in ensuring patient safety during drug design
studies. While traditional preclinical studies have historically relied on animal models to …

Comparative Toxicogenomics Database: a knowledgebase and discovery tool for chemical–gene–disease networks

AP Davis, CG Murphy… - Nucleic acids …, 2009 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD) is a curated database that
promotes understanding about the effects of environmental chemicals on human health …

Keblm: Knowledge-enhanced biomedical language models

TM Lai, CX Zhai, H Ji - Journal of Biomedical Informatics, 2023 - Elsevier
Pretrained language models (PLMs) have demonstrated strong performance on many
natural language processing (NLP) tasks. Despite their great success, these PLMs are …

DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene–disease networks

A Bauer-Mehren, M Rautschka, F Sanz… - …, 2010 - academic.oup.com
DisGeNET is a plugin for Cytoscape to query and analyze human gene–disease networks.
DisGeNET allows user-friendly access to a new gene–disease database that we have …