Polygenic Scores and Preclinical Cardiovascular Disease in Individuals With HIV: Insights From the REPRIEVE Trial

RS Zou, Y Ruan, B Truong, R Bhattacharya… - Journal of the …, 2024 - Am Heart Assoc
Background Coronary artery disease (CAD) is a leading cause of death among the 38.4
million people with HIV globally. The extent to which cardiovascular polygenic risk scores …

Polygenic risk scores for prediction of subclinical coronary artery disease in persons with human immunodeficiency virus (HIV): the Swiss HIV cohort study

IC Schoepf, CW Thorball, H Kovari… - Clinical Infectious …, 2023 - academic.oup.com
Background In people with human immunodeficiency virus (HIV)(PWH), individual polygenic
risk scores (PRSs) are associated with coronary artery disease (CAD) events. Whether …

The association of HIV-specific risk factors with cardiovascular events in addition to traditional risk factors in people living with HIV

L Mavarani, N Reinsch, S Albayrak-Rena… - AIDS Research and …, 2024 - liebertpub.com
Traditional cardiovascular risk scores underestimate the incidence of cardiovascular
diseases (CVD) in people living with HIV (PLH). This study compared the effect of HIV …

Distinct inflammatory profiles linked to cardiovascular disease risk in HIV infection: implications for the design of preventive and therapeutic interventions

J Laurence, DL Winslow - AIDS, 2023 - journals.lww.com
Cardiovascular disease (CVD) is the third most frequent non-AIDS cause of death in people
with HIV (PWH), and, in those on combination antiretroviral therapy (cART), it is the leading …

HIV and Cardiovascular Disease: The Unmeasured Risk

T Heseltine - 2023 - search.proquest.com
CVD is an emerging health economic emergency. Following the successful introduction of
ART, PLWHIV have a close to normal life expectancy and are succumbing to traditional …

Subclinical atherosclerosis burden in carotid and femoral territories in HIV subjects: relationships with HIV and non-HIV related factors

P Ferrer, L López, J Pérez, N Cabello, MJ Núñez… - BMC Infectious …, 2024 - Springer
Background Cardiovascular disease is a major cause of morbidity in an aging HIV
population. However, risk estimation with the most frequent equations usually classifies HIV …