Ferroptosis is an iron-and lipid peroxidation-dependent cell death modality and emerging
evidence indicates that ferroptosis has great explanatory potential for neuronal loss and …

A failure in redox homeostasis is a common hallmark of Alzheimer's Disease (AD) and
Parkinson's Disease (PD), two age-dependent neurodegenerative disorders (NDD), causing …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates
hundreds of antioxidant genes, and is activated in response to oxidative stress. Given that …

Efforts have been made to understand the physiological and pathological role of DJ-1, a
Parkinson's disease (PD)-associated protein, to provide new insights into PD …

Significance: The lack of disease-modifying treatments for Alzheimer's disease (AD) that
substantially alter the course of the disease highlights the need for new biological models of …

Ischemic stroke is associated with a surge in reactive oxygen species generation during
reperfusion. The narrow therapeutic window for the delivery of intravenous thrombolysis and …

A series of water-soluble sodium salts of 3-formyl-4-hydroxybenzenesulfonic acid
thiosemicarbazones (or sodium 5-sulfonate-salicylaldehyde thiosemicarbazones) …

Several mutations in the gene coding for DJ-1 have been associated with early onset forms
of parkinsonism. In spite of the massive effort spent by the scientific community in …

Ruthenium (Ru) is one of the most promising metals for its versatility in driving a wide range
of catalytic reactions. However, owing to the intrinsic preference of hexagonal close-packed …

Currently, combining biodegradable polymeric scaffolds with living cells for bone repair has
received significant attention. Ideal bone tissue engineering scaffolds should be …