Oxidation of LDL and its clinical implication

E Matsuura, GRV Hughes, MA Khamashta - Autoimmunity reviews, 2008 - Elsevier
Oxidative modification of low-density lipoprotein (LDL) is one of the earliest events in
atherosclerosis. Oxidized LDL (oxLDL) represents a variety of modification of both lipid and …

Antiphospholipid antibodies and thrombosis

M Greaves - The Lancet, 1999 - thelancet.com
Antiphospholipid antibodies are associated with arterial and venous thrombosis, recurrent
pregnancy loss, and thrombocytopenia. Although the antibodies have not been conclusively …

Bacterial induction of autoantibodies to β2-glycoprotein-I accounts for the infectious etiology of antiphospholipid syndrome

M Blank, I Krause, M Fridkin, N Keller… - The Journal of …, 2002 - Am Soc Clin Investig
The antiphospholipid syndrome (APS) is characterized by the presence of pathogenic
autoantibodies against β2-glycoprotein-I (β2GPI). The factors causing production of anti …

Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface.

E Matsuura, Y Igarashi, T Yasuda, DA Triplett… - The Journal of …, 1994 - rupress.org
Anticardiolipin antibodies (aCL) derived from the sera of individuals exhibiting the
antiphospholipid syndrome (APS) directly bind to beta 2-glycoprotein I (beta 2-GPI), which is …

Association of autoantibodies against the phosphatidylserine–prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of …

T Atsumi, M Ieko, ML Bertolaccini… - … : Official Journal of …, 2000 - Wiley Online Library
Objective To clarify the association of autoantibodies against prothrombin with the clinical
manifestations of the antiphospholipid syndrome (APS) and with the presence of lupus …

Involvement of β2-glycoprotein I and anticardiolipin antibodies in oxidatively modified low-density lipoprotein uptake by macrophages

Y Hasunuma, E Matsuura, Z Makita… - Clinical & …, 1997 - academic.oup.com
Anticardiolipin antibodies (aCL) in the sera of patients with antiphospholipid syndrome
(APS) recognize an altered structure of β2-glycoprotein I (β2-GPI) interacting with solid …

Cardiolipin interactions with proteins

J Planas-Iglesias, H Dwarakanath, D Mohammadyani… - Biophysical journal, 2015 - cell.com
Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria
with four acyl chains and two phosphate groups that have been implicated in numerous …

Antiphospholipid syndrome: an overview

JG Hanly - Cmaj, 2003 - Can Med Assoc
ANTIPHOSPHOLIPID ANTIBODIES ARE A HETEROGENEOUS GROUP of autoantibodies
that are detected by immunoassays and functional coagulation tests. The antigenic targets …

Oxidative modification of low-density lipoprotein and immune regulation of atherosclerosis

E Matsuura, K Kobayashi, M Tabuchi… - Progress in lipid research, 2006 - Elsevier
Oxidized low-density lipoprotein (oxLDL) is thought to promote atherosclerosis through
complex inflammatory and immunologic mechanisms that lead to lipid dysregulation and …

Circulating oxidized LDL forms complexes with β2-glycoprotein I: implication as an atherogenic autoantigen

K Kobayashi, M Kishi, T Atsumi, ML Bertolaccini… - Journal of lipid …, 2003 - ASBMB
β 2-glycoprotein I (β 2-GPI) is a major antigen for antiphospholipid antibodies (Abs, aPL)
present in patients with antiphospholipid syndrome (APS). We recently reported (J. Lipid …