MRI of healthy brain aging: A review

ME MacDonald, GB Pike - NMR in Biomedicine, 2021 - Wiley Online Library
We present a review of the characterization of healthy brain aging using MRI with an
emphasis on morphology, lesions, and quantitative MR parameters. A scope review found …

The psychobiology of neglect

MD De Bellis - Child maltreatment, 2005 - journals.sagepub.com
Child neglect, the most prevalent form of child maltreatment, is associated with adverse
psychological and educational outcomes. It is hypothesized that these outcomes may be …

Marked loss of myelinated nerve fibers in the human brain with age

L Marner, JR Nyengaard, Y Tang… - Journal of comparative …, 2003 - Wiley Online Library
The white matter is the structure of the brain that declines most with age—almost 30%, but
little is known about the age‐effect on the fibers that constitute the white matter. In the …

Diffusion tensor imaging and aging

EV Sullivan, A Pfefferbaum - Neuroscience & Biobehavioral Reviews, 2006 - Elsevier
Magnetic resonance diffusion tensor imaging (DTI) is a non-invasive in vivo method for
characterizing the integrity of anatomical connections and white matter circuitry and provides …

Aging white matter and cognition: differential effects of regional variations in diffusion properties on memory, executive functions, and speed

KM Kennedy, N Raz - Neuropsychologia, 2009 - Elsevier
Disruption of cerebral white matter has been proposed as an explanation for age-related
cognitive declines. However, the role of specific regions in specific cognitive declines …

Quantitative fiber tracking of lateral and interhemispheric white matter systems in normal aging: relations to timed performance

EV Sullivan, T Rohlfing, A Pfefferbaum - Neurobiology of aging, 2010 - Elsevier
The integrity of white matter, as measured in vivo with diffusion tensor imaging (DTI), is
disrupted in normal aging. A current consensus is that in adults advancing age affects …

White matter microstructural integrity and cognitive function in a general elderly population

MW Vernooij, MA Ikram, HA Vrooman… - Archives of general …, 2009 - jamanetwork.com
Context The role of macrostructural white matter changes, such as atrophy and white matter
lesions, in cognitive decline is increasingly being recognized. However, in the elderly …

MR diffusion tensor imaging: a window into white matter integrity of the working brain

S Chanraud, N Zahr, EV Sullivan… - Neuropsychology review, 2010 - Springer
Abstract As Norman Geschwind asserted in 1965, syndromes resulting from white matter
lesions could produce deficits in higher-order functions and “disconnexion” or the …

Problem solving, working memory, and motor correlates of association and commissural fiber bundles in normal aging: a quantitative fiber tracking study

NM Zahr, T Rohlfing, A Pfefferbaum, EV Sullivan - Neuroimage, 2009 - Elsevier
Normal aging is accompanied by decline in selective cognitive and motor functions. A
concurrent decline in regional white matter integrity, detectable with diffusion tensor imaging …

Diffusion imaging of brain tumors

SE Maier, Y Sun, RV Mulkern - NMR in biomedicine, 2010 - Wiley Online Library
MRI offers a tremendous armamentarium of different methods that can be employed in brain
tumor characterization. MR diffusion imaging has become a widely accepted method to …