The T cell memory response is a crucial component of adaptive immunity responsible for
limiting or preventing viral reinfection. T cell memory after infection with the SARS-CoV-2 …

Coronaviruses regularly cause outbreaks of zoonotic diseases characterized by severe
pneumonia. The new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS …

There has been substantial research on adult COVID-19 and how to treat it. But how do
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections afflict children …

The upper airway is an important site of infection, but immune memory in the human upper
airway is poorly understood, with implications for COVID-19 and many other human …

CD8+ T cells provide robust antiviral immunity, but how epitope-specific T cells evolve
across the human lifespan is unclear. Here we defined CD8+ T cell immunity directed at the …

Background: Patients affected by different types of autoimmune diseases, including common
conditions such as multiple sclerosis (MS) and rheumatoid arthritis (RA), are often treated …

High-risk groups, including Indigenous people, are at risk of severe COVID-19. Here we
found that Australian First Nations peoples elicit effective immune responses to COVID-19 …

Immunocompromised hematology patients are vulnerable to severe COVID-19 and respond
poorly to vaccination. Relative deficits in immunity are, however, unclear, especially after 3 …

Abstract Objectives High‐magnitude CD8+ T cell responses are associated with mild COVID‐
19 disease; however, the underlying characteristics that define CD8+ T cell‐mediated …

During the three years since SARS-CoV-2 infections were first described a wealth of
information has been gathered about viral variants and their changing properties, the …