The need for better antifungal therapy is commonly accepted in view of the high mortality
rates associated with systemic infections, the low number of available antifungal classes …

Coccidioidomycosis (CM) and paracoccidioidomycosis (PCM) are systemic mycoses that
are highly endemic in Latin America and have recently been included on the World Health …

Background: Paracoccidioidomycosis (PCM) is a chronic disease that causes sequelae and
requires prolonged treatment; therefore, new therapeutic approaches are necessary. In view …

Fungal infections are emerging as a major problem in part due to high mortality associated
with systemic infections, especially in the case of immunocompromised patients. With the …

The release of extracellular vesicles (EVs) by fungi is a fundamental cellular process. EVs
carry several biomolecules, including pigments, proteins, enzymes, lipids, nucleic acids, and …

Extracellular vesicles (EVs) are a heterogeneous group of lipid membrane-enclosed
compartments that contain different biomolecules and are released by almost all living cells …

Vaccination is one of the greatest public health achievements in the past century, protecting
and improving the quality of life of the population worldwide. However, a safe and effective …

The invasive fungal infections (IFIs) are a major cause of mortality due to infectious disease
worldwide. Majority of the IFIs are caused by opportunistic fungi including Candida …

Paracoccidioidomycosis (PCM), caused by Paracoccidioides spp, is an important endemic
mycosis in Latin America. There are two recognized Paracoccidioides species, P …

Dimorphic fungi are agents of systemic mycoses associated with significant morbidity and
frequent lethality in the Americas. Among the pathogenic species are Paracoccidioides …