Gadolinium retention: a research roadmap from the 2018 NIH/ACR/RSNA workshop on gadolinium chelates
Gadolinium-based contrast agents (GBCAs) have revolutionized MRI, enabling physicians
to obtain crucial life-saving medical information that often cannot be obtained with other …
to obtain crucial life-saving medical information that often cannot be obtained with other …
Gadolinium: pharmacokinetics and toxicity in humans and laboratory animals following contrast agent administration
J Davies, P Siebenhandl-Wolff, F Tranquart… - Archives of …, 2022 - Springer
Gadolinium-based contrast agents (GBCAs) have transformed magnetic resonance imaging
(MRI) by facilitating the use of contrast-enhanced MRI to allow vital clinical diagnosis in a …
(MRI) by facilitating the use of contrast-enhanced MRI to allow vital clinical diagnosis in a …
The biological fate of gadolinium-based MRI contrast agents: a call to action for bioinorganic chemists
Gadolinium-based contrast agents (GBCAs) are widely used with clinical magnetic
resonance imaging (MRI), and 10 s of millions of doses of GBCAs are administered annually …
resonance imaging (MRI), and 10 s of millions of doses of GBCAs are administered annually …
Mn2+ Bispidine Complex Combining Exceptional Stability, Inertness, and MRI Efficiency
D Ndiaye, P Cieslik, H Wadepohl, A Pallier… - Journal of the …, 2022 - ACS Publications
As an essential metal ion and an efficient relaxation agent, Mn2+ holds a great promise to
replace Gd3+ in magnetic resonance imaging (MRI) contrast agent applications, if its stable …
replace Gd3+ in magnetic resonance imaging (MRI) contrast agent applications, if its stable …
Mn (II) compounds as an alternative to Gd-based MRI probes
Mn (II) has several favorable physicochemical characteristics and a good toxicity profile,
which makes it a viable alternative to the Gd (III)-based MRI contrast agents currently used in …
which makes it a viable alternative to the Gd (III)-based MRI contrast agents currently used in …
Ten years of gadolinium retention and deposition: ESMRMB-GREC looks backward and forward
AJ van der Molen, CC Quattrocchi, CA Mallio… - European …, 2024 - Springer
In 2014, for the first time, visible hyperintensities on unenhanced T1-weighted images in the
nucleus dentatus and globus pallidus of the brain were associated with previous Gadolinium …
nucleus dentatus and globus pallidus of the brain were associated with previous Gadolinium …
Magnetic materials and systems: Domain structure visualization and other characterization techniques for the application in the materials science and biomedicine
Magnetic structures have attracted a great interest due to their multiple applications, from
physics to biomedicine. Several techniques are currently employed to investigate magnetic …
physics to biomedicine. Several techniques are currently employed to investigate magnetic …
Unprecedented Kinetic Inertness for a Mn2+‐Bispidine Chelate: A Novel Structural Entry for Mn2+‐Based Imaging Agents
D Ndiaye, M Sy, A Pallier, S Même… - Angewandte Chemie …, 2020 - Wiley Online Library
The search for more biocompatible alternatives to Gd3+‐based MRI agents, and the interest
in 52Mn for PET imaging call for ligands that form inert Mn2+ chelates. Given the labile …
in 52Mn for PET imaging call for ligands that form inert Mn2+ chelates. Given the labile …
Structural Variations in Carboxylated Bispidine Ligands: Influence of Positional Isomerism and Rigidity on the Conformation, Stability, Inertness and Relaxivity of their …
D Ndiaye, M Sy, W Thor… - … A European Journal, 2023 - Wiley Online Library
Abstract Mn2+ complexes of 2, 4‐pyridyl‐disubstituted bispidine ligands have emerged as
more biocompatible alternatives to Gd3+‐based MRI probes. They display relaxivities …
more biocompatible alternatives to Gd3+‐based MRI probes. They display relaxivities …
Skin toxicity after exposure to gadolinium-based contrast agents in normal renal function, using clinical approved doses: current status of preclinical and clinical …
Objectives The aim of this study was to summarize the current preclinical and clinical
evidence on the association between exposure to gadolinium (Gd) compounds and skin …
evidence on the association between exposure to gadolinium (Gd) compounds and skin …