Emerging evidence points to a strong association between the gut microbiota and the risk,
development and progression of gastrointestinal cancers such as colorectal cancer (CRC) …

While metabolic reprogramming of cancer cells has long been considered from the
standpoint of how and why cancer cells preferentially utilize glucose via aerobic glycolysis …

Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …

The gut microbiota is associated with metabolic diseases including obesity, insulin
resistance, and nonalcoholic fatty liver disease, as shown by correlative studies and by …

This review will focus on how bile acids are being used in clinical trials to treat neurological
diseases due to their central involvement with the gut-liver-brain axis and their physiological …

Portal blood flows into the liver containing the gut microbiome and its products such as
endotoxin and bacterial DNA. The cirrhotic liver acts and detoxifies as the initial site of …

Accumulating evidence supports that gut dysbiosis may relate to various liver diseases.
Alcoholics with high intestinal permeability had a decrease in the abundance of …

The human gastrointestinal tract colonizes a large number of microbial microflora, forms a
host-microbiota co-metabolism structure with the host to participate in various metabolic …

Purpose Cholecystectomy (XGB) is widely recognized as a risk factor for colon cancer (CC).
Continuous exposure of the colonic epithelium to deoxycholic acid (DCA) post-XGB may …

Farnesoid X receptor (FXR, encoded by NR1H4), a critical regulator of bile acid
homeostasis, is widely implicated in human tumorigenesis. However, the functional role of …