ABSTRACT A growing amount of evidence has supported that gut microbiota plays a vital
role in the reproductive endocrine system throughout a woman's whole life, and gut …

There is currently accumulating evidence that endogenous estrogens play a critical role in
the development of breast cancer. Estrogens and their metabolites have been studied in …

The present review discusses recent work on melatonin-mediated circadian regulation, the
metabolic and molecular signaling mechanisms that are involved in human breast cancer …

Long-term exposure to excess estrogen increases the risk of breast cancer and type 1
endometrial cancer. Most of the estrogen in premenopausal women is synthesized by the …

In mammals, secretin is a 27-amino acid peptide that was first studied in 1902 by Bayliss
and Starling from the extracts of the jejunal mucosa for its ability to stimulate pancreatic …

Many inflammation-associated diseases, including cancers, increase in women after
menopause and with obesity. In contrast to anti-inflammatory actions of 17β-estradiol, we …

Globally, human papilloma virus (HPV) infection is a common sexually transmitted disease.
However, most of the HPV infections eventually resolve aided by the body's efficient cell …

The study of large prospective collections of plasma samples from women prior to the
development of breast cancer has firmly established certain sex steroids as being …

Breast cancer is the most prevalent type of cancer in women and responsible for significant
female cancer-related mortality worldwide. In the Western world, over 80% of breast cancers …

Following their successful implementation for the treatment of metastatic breast cancer, the
'third-generation'aromatase inhibitors (anastrozole, letrozole, and exemestane) have now …