Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: comorbidity between depression and neurodegenerative disorders
Given the array of biological changes induced by stressors, it is not surprising that these
experiences may provoke a variety of illnesses. Among others things, stressors promote …
experiences may provoke a variety of illnesses. Among others things, stressors promote …
Neuroprotective actions of melanocortins: a therapeutic opportunity
A Catania - Trends in neurosciences, 2008 - cell.com
α-Melanocyte stimulating hormone (α-MSH) and other melanocortins make up a family of
endogenous peptides derived from pro-opiomelanocortin. Through binding to five …
endogenous peptides derived from pro-opiomelanocortin. Through binding to five …
Mechanically adaptive nanocomposites for neural interfacing
The recording of neural signals with microelectrodes that are implanted into the cortex of the
brain is potentially useful for a range of clinical applications. However, the widespread use …
brain is potentially useful for a range of clinical applications. However, the widespread use …
Activation of melanocortin 4 receptors reduces the inflammatory response and prevents apoptosis induced by lipopolysaccharide and interferon-γ in astrocytes
α-MSH exerts an immunomodulatory action in the brain and may play a neuroprotective role
acting through melanocortin 4 receptors (MC4Rs). In the present study, we show that …
acting through melanocortin 4 receptors (MC4Rs). In the present study, we show that …
Single administration of tripeptide α-MSH (11–13) attenuates brain damage by reduced inflammation and apoptosis after experimental traumatic brain injury in mice
EV Schaible, A Steinsträßer, A Jahn-Eimermacher… - PloS one, 2013 - journals.plos.org
Following traumatic brain injury (TBI) neuroinflammatory processes promote neuronal cell
loss. Alpha-melanocyte-stimulating hormone (α-MSH) is a neuropeptide with …
loss. Alpha-melanocyte-stimulating hormone (α-MSH) is a neuropeptide with …
Melanocortin 4 receptor activation induces brain-derived neurotrophic factor expression in rat astrocytes through cyclic AMP–Protein kinase A pathway
C Caruso, L Carniglia, D Durand, PV Gonzalez… - Molecular and cellular …, 2012 - Elsevier
Melanocortin 4 receptors (MC4R) are mainly expressed in the brain. We previously showed
that the anti-inflammatory action of α-melanocyte-stimulating hormone (α-MSH) in rat …
that the anti-inflammatory action of α-melanocyte-stimulating hormone (α-MSH) in rat …
The melanocortin system in leukocyte biology
A Catania - Journal of Leucocyte Biology, 2007 - academic.oup.com
The melanocortin system is composed of the melanocortin peptides, adrenocorticotropic
hormone and α-, β-, and γ-melanocyte-stimulating hormone, the melanocortin receptors …
hormone and α-, β-, and γ-melanocyte-stimulating hormone, the melanocortin receptors …
Melanocortin-4 receptor-mediated inhibition of apoptosis in immortalized hypothalamic neurons via mitogen-activated protein kinase
B Chai, JY Li, W Zhang, E Newman, J Ammori… - Peptides, 2006 - Elsevier
The melanocortin-4 receptor (MC4R) is a seven transmembrane member of the
melanocortin receptor family. The GT1-1 cell line exhibits endogenous expression of MC4R …
melanocortin receptor family. The GT1-1 cell line exhibits endogenous expression of MC4R …
Effect of NDP-α-MSH on PPAR-γ and–β expression and anti-inflammatory cytokine release in rat astrocytes and microglia
Brain inflammation plays a central role in numerous brain pathologies. Microglia and
astrocytes are the main effector cells that become activated when an inflammatory process …
astrocytes are the main effector cells that become activated when an inflammatory process …
Role of α-melanocyte stimulating hormone and melanocortin 4 receptor in brain inflammation
M Lasaga, L Debeljuk, D Durand, TN Scimonelli… - Peptides, 2008 - Elsevier
Inflammatory processes contribute widely to the development of neurodegenerative
diseases. The expression of many inflammatory mediators was found to be increased in …
diseases. The expression of many inflammatory mediators was found to be increased in …