Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma
Y Miao, GL Zhao, S Cheng, Z Wang, XL Yang - Progress in retinal and eye …, 2023 - Elsevier
Elevation of intraocular pressure (IOP) is a major risk factor for neurodegeneration in
glaucoma. Glial cells, which play an important role in normal functioning of retinal neurons …
glaucoma. Glial cells, which play an important role in normal functioning of retinal neurons …
Association between glaucoma susceptibility with combined defects in mitochondrial oxidative phosphorylation and fatty acid beta oxidation
Glaucoma is one of the leading causes of visual impairment and blindness worldwide, and
is characterized by the progressive damage of retinal ganglion cells (RGCs) and the atrophy …
is characterized by the progressive damage of retinal ganglion cells (RGCs) and the atrophy …
Role of the mtDNA mutations and mitophagy in inflammaging
SA Dabravolski, NG Nikiforov, AD Zhuravlev… - International Journal of …, 2022 - mdpi.com
Ageing is an unavoidable multi-factorial process, characterised by a gradual decrease in
physiological functionality and increasing vulnerability of the organism to environmental …
physiological functionality and increasing vulnerability of the organism to environmental …
Serum IL-6/IL-10 ratio as a biomarker for the diagnosis and severity assessment of primary-open angle glaucoma
Objective: To assess the performance of serum cytokine IL-6 and IL-6/IL-10 ratio as
biomarkers for the diagnosis of primary open-angle glaucoma (POAG) and for determining …
biomarkers for the diagnosis of primary open-angle glaucoma (POAG) and for determining …
Fallopia Japonica and Prunella vulgaris inhibit myopia progression by suppressing AKT and NFκB mediated inflammatory reactions
CS Chen, YA Hsu, CH Lin, YC Wang, ES Lin… - … Medicine and Therapies, 2022 - Springer
Background The increased global incidence of myopia requires the establishment of
therapeutic approaches. This study aimed to investigate the effect of Fallopia Japonica (FJ) …
therapeutic approaches. This study aimed to investigate the effect of Fallopia Japonica (FJ) …
The Multifaceted Non-Genetic Risk Factors for Primary Open-Angle Glaucoma-An Overview of Systematic Reviews
J Rovelt, J Freiberg, A Azuara-Blanco, G Virgili… - Ophthalmology …, 2024 - Elsevier
Topic A synthesis of the current knowledge on risk factors for primary open-angle glaucoma
(POAG). Method We conducted a systematic search of PubMed, Embase, Web of Science …
(POAG). Method We conducted a systematic search of PubMed, Embase, Web of Science …
The diagnostic accuracy of seven commercial molecular in vitro SARS-CoV-2 detection tests: a rapid meta-analysis
Objective To compare the accuracy parameters of seven commercial molecular in vitro
diagnostic tests for detecting SARS-CoV-2. Methods Studies evaluating the accuracy of …
diagnostic tests for detecting SARS-CoV-2. Methods Studies evaluating the accuracy of …
Polymorphisms of the dopamine metabolic and signaling pathways are associated with susceptibility to motor levodopa-induced complications (MLIC) in Parkinson's …
Background Dopamine replacement therapy remains the gold standard for symptomatic
management of Parkinson's disease worldwide. However, most patients will develop …
management of Parkinson's disease worldwide. However, most patients will develop …
A systematic proteomic profiling and pathway analysis of protein biomarkers in diabetic retinopathy with subsequent validation of the IL-6 upstream regulator
ZS Ulhaq, YTN Hasan, NK Rosyidin, LA Istifiani… - Journal of Diabetes & …, 2023 - Springer
Purpose Diabetic retinopathy (DR) is a leading cause of irreversible blindness worldwide.
Identifying risk factors associated with DR development and progression is crucial for …
Identifying risk factors associated with DR development and progression is crucial for …
A common secretomic signature across epithelial cancers metastatic to the pleura supports IL-6 axis therapeutic targeting
VS Donnenberg, JD Luketich, B Popov… - Frontiers in …, 2024 - frontiersin.org
Background Many cancers metastasize to the pleura, resulting in effusions that cause
dyspnea and discomfort. Regardless of the tissue of origin, pleural malignancies are …
dyspnea and discomfort. Regardless of the tissue of origin, pleural malignancies are …