Immunosequencing is a platform technology that allows the enumeration, specification and
quantification of each and every B-and/or T-cell in any biologic sample of interest. Thus, it …

IMGT®, the international ImMunoGeneTics® information system founded in 1989 by Marie-
Paule Lefranc (Université de Montpellier and CNRS), marked the advent of …

Focal radiation therapy enhances systemic responses to anti-CTLA-4 antibodies in
preclinical studies and in some patients with melanoma,–, but its efficacy in inducing …

The discovery of the highly efficient site-specific nuclease system CRISPR–Cas9 from
Streptococcus pyogenes has galvanized the field of gene therapy,. The immunogenicity of …

Relapse after allogeneic hematopoietic cell transplantation (HCT) is the leading cause of
death in patients with acute myeloid leukemia (AML) entering HCT with poor-risk features …

An individual's T cell repertoire dynamically encodes their pathogen exposure history. To
determine whether pathogen exposure signatures can be identified by documenting public T …

The variable domain of an immunoglobulin (IG) sequence is encoded by multiple genes,
including the variable (V) gene, the diversity (D) gene and the joining (J) gene. Analysis of …

IMGT®, the international ImMunoGeneTics information system®(http://www. imgt. org) is the
global reference in immunogenetics and immunoinformatics. By its creation in 1989 by …

T and B cell receptor loci undergo combinatorial rearrangement, generating a diverse
immune receptor repertoire, which is vital for recognition of potential antigens. Here we use …

Abstract γδ T cells are considered to be innate-like lymphocytes that respond rapidly to
stress without clonal selection and differentiation. Here we use next-generation sequencing …