COVID-19 therapeutics: Challenges and directions for the future

PC Robinson, DFL Liew, HL Tanner… - Proceedings of the …, 2022 - National Acad Sciences
The emergence of SARS-CoV-2 triggering the COVID-19 pandemic ranks as arguably the
greatest medical emergency of the last century. COVID-19 has highlighted health disparities …

Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis

S Akiyama, S Hamdeh, D Micic… - Annals of the rheumatic …, 2021 - ard.bmj.com
Objectives The prevalence and clinical outcomes of COVID-19 in patients with autoimmune
diseases who are frequently treated with disease modifying therapies remains poorly …

Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician …

M Gianfrancesco, KL Hyrich, S Al-Adely… - Annals of the …, 2020 - ard.bmj.com
Objectives COVID-19 outcomes in people with rheumatic diseases remain poorly
understood. The aim was to examine demographic and clinical factors associated with …

COVID-19 in patients with systemic lupus erythematosus: lessons learned from the inflammatory disease

R Fernandez-Ruiz, JL Paredes, TB Niewold - Translational Research, 2021 - Elsevier
As the world navigates the coronavirus disease 2019 (COVID-19) pandemic, there is a
growing need to assess its impact in patients with autoimmune rheumatic diseases, such as …

Update I. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19

A Cortegiani, M Ippolito, G Ingoglia, P Iozzo… - Journal of critical …, 2020 - Elsevier
Purpose To assess efficacy and safety of chloroquine (CQ)/hydroxychloroquine (HCQ) for
treatment or prophylaxis of COVID-19 in adult humans. Materials and methods MEDLINE …

Hydroxychloroquine: a comprehensive review and its controversial role in coronavirus disease 2019

P Bansal, A Goyal, A Cusick Iv, S Lahan… - Annals of …, 2021 - Taylor & Francis
Hydroxychloroquine, initially used as an antimalarial, is used as an immunomodulatory and
anti-inflammatory agent for the management of autoimmune and rheumatic diseases such …

High levels of immunosuppression are related to unfavourable outcomes in hospitalised patients with rheumatic diseases and COVID-19: first results of ReumaCoV …

CDL Marques, AM Kakehasi, MM Pinheiro… - RMD open, 2021 - rmdopen.bmj.com
Objectives To evaluate risk factors associated with unfavourable outcomes: emergency care,
hospitalisation, admission to intensive care unit (ICU), mechanical ventilation and death in …

Leveraging the United States epicenter to provide insights on COVID‐19 in patients with systemic lupus erythematosus

R Fernandez‐Ruiz, M Masson, MY Kim… - Arthritis & …, 2020 - Wiley Online Library
Objective To characterize patients with systemic lupus erythematosus (SLE) affected by
coronavirus disease 2019 (COVID‐19) and to analyze associations of comorbidities and …

Swinging the pendulum: lessons learned from public discourse concerning hydroxychloroquine and COVID-19

SE Sattui, JW Liew, ER Graef… - Expert Review of …, 2020 - Taylor & Francis
Introduction Several months into the COVID-19 pandemic, safe and effective treatments
against this global health disaster have yet to be identified. Clinical research trials around …

Incidence of COVID-19 hospitalisation in patients with systemic lupus erythematosus: a nationwide cohort study from Denmark

R Cordtz, S Kristensen, LPH Dalgaard… - Journal of clinical …, 2021 - mdpi.com
Background: Patients with systemic lupus erythematosus (SLE) have an increased risk of
infections due to impaired immune functions, disease activity, and treatment. This study …