Biological properties of hexadeca-substituted metal phthalocyanines bearing different functional groups

N Farajzadeh, S Özdemir, G Tollu, ZA Bayır… - Journal of Inorganic …, 2022 - Elsevier
In this study, a new tetra-substituted phthalonitrile (diethyl 2-(2-chloro-4, 5-dicyano-3, 6-bis
(hexyloxy) phenyl) malonate) bearing three different substituents was synthesized and …

The design and synthesis of metallophthalocyanine–gold nanoparticle hybrids as biological agents

N Farajzadeh, J Aftab, HY Yenilmez… - New Journal of …, 2022 - pubs.rsc.org
This study presents the synthesis of 4-2-(4-ethynyl-N, N-dimethylaniline) phthalonitrile (1)
and its new peripherally tetra-substituted metal phthalocyanines {M= Co (2), Zn (3)} …

Exploring improved strategies for therapeutic studies and biological activities of novel zinc and indium phthalocyanines

K Celep, GY Atmaca, PD Aydoğmuş, K Eroğlu… - Dalton …, 2024 - pubs.rsc.org
This study investigates novel zinc and indium phthalocyanines with Schiff base and sulphur
moieties, focusing on their potential for cancer therapy and antimicrobial applications. It …

Novel axially symmetric and unsymmetric silicon (iv) phthalocyanines having anti-inflammatory groups: synthesis, characterization and their biological properties

GG Çelik, S Gonca, B Şahin, S Özdemir, D Atilla… - Dalton …, 2022 - pubs.rsc.org
New asymmetric Si (IV) Pc (1), monomeloxicammonotriethyleneglycolmon…
(phthalocyaninano) silicone, axially ligated with meloxicam as a non-steroidal anti …

Effect of axial ligand length on biological and anticancer properties of axially disubstituted silicon phthalocyanines

HY Yenilmez, N Farajzadeh… - Chemistry & …, 2023 - Wiley Online Library
In this study, three new axially disubstituted silicon phthalocyanines (SiPc1–3) and their
quaternized phthalocyanine derivatives (QSiPc1–3) were prepared and characterized. The …

Synthesis and biological evaluation of novel zinc (II) and nickel (II) phthalocyanines as cholinesterase inhibitors

D Akkaya, B Barut, S Sari, R Reis, H Fazli… - Journal of …, 2023 - Elsevier
Alzheimer's disease (AD) is one of the irreversible neurodegenerative disorders among
older people and causes behavior, memory and thinking problems. In this study, peripheral …

Synthesis, characterization, and α‐glucosidase, cholinesterases, and tyrosinase inhibitory effects of axial substituted silicon and peripheral tetra‐substituted copper (II) …

BA Öztürmen, B Barut… - Applied Organometallic …, 2022 - Wiley Online Library
In this paper, we have synthesized axially di‐(3, 3‐diphenylpropoxy) substituted silicon (DFP‐
Si) and peripherally tetra‐(3, 3‐diphenylpropoxy) substituted copper (II), manganese (III) …

In-silico Molecular Docking and ADMET predictions of Pyrido[2,3-d]pyrimidine-2,4(1H,3H)-Dione Analogues as promising Antimicrobial, Antioxidant and Anticancer …

M Sivanandhan, A Parasuraman - Polycyclic Aromatic Compounds, 2024 - Taylor & Francis
Pyridopyrimidine are heterocyclic molecules enclosing fused pyridine and pyrimidine rings.
Owing to its fascinating core structure and pharmacological applications a series of 7-([1 …

Synthesis, photophysical and photochemical properties of unsymmetrical zinc (II) phthalocyanines bearing 8-hydroxyquinoline unit

E Ahmetali, B Yıldız, EE Ahi, M Durmuş, MK Şener - Polyhedron, 2022 - Elsevier
Hydroxyquinolines (8-HQs) are very important molecules in the field of biochemistry. They
may play different roles due to their chelating ability. Especially, its interaction with different …

Synthesis, photo-physicochemical and biological properties of novel tetrahydropyrimidone-substituted metallo-phthalocyanines

K Harmandar, EN Kaya, G Tollu, IF Sengul… - Dalton …, 2024 - pubs.rsc.org
In this study, new peripherally substituted symmetric zinc and magnesium phthalocyanines
(4 and 5) were successfully prepared by cyclotetramerization of the tetrahydropyrimidone …