Spatial and temporal activation of spinal glial cells: role of gliopathy in central neuropathic pain following spinal cord injury in rats

YS Gwak, J Kang, GC Unabia, CE Hulsebosch - Experimental neurology, 2012 - Elsevier
In the spinal cord, neuron and glial cells actively interact and contribute to neurofunction.
Surprisingly, both cell types have similar receptors, transporters and ion channels and also …

GABA and central neuropathic pain following spinal cord injury

YS Gwak, CE Hulsebosch - Neuropharmacology, 2011 - Elsevier
Spinal cord injury induces maladaptive synaptic transmission in the somatosensory system
that results in chronic central neuropathic pain. Recent literature suggests that glial-neuronal …

Sex-dependent glial signaling in pathological pain: distinct roles of spinal microglia and astrocytes

G Chen, X Luo, MY Qadri, T Berta, RR Ji - Neuroscience bulletin, 2018 - Springer
Increasing evidence suggests that spinal microglia regulate pathological pain in males. In
this study, we investigated the effects of several microglial and astroglial modulators on …

Priming of adult pain responses by neonatal pain experience: maintenance by central neuroimmune activity

S Beggs, G Currie, MW Salter, M Fitzgerald, SM Walker - Brain, 2012 - academic.oup.com
Adult brain connectivity is shaped by the balance of sensory inputs in early life. In the case of
pain pathways, it is less clear whether nociceptive inputs in infancy can have a lasting …

Borneol, a bicyclic monoterpene alcohol, reduces nociceptive behavior and inflammatory response in mice

JRGS Almeida, GR Souza, JC Silva… - The Scientific World …, 2013 - Wiley Online Library
Borneol, a bicyclic monoterpene, has been evaluated for antinociceptive and anti‐
inflammatory activities. Antinociceptive and anti‐inflammatory activities were studied by …

Minocycline prevents the development of neuropathic pain, but not acute pain: possible anti-inflammatory and antioxidant mechanisms

SSV Padi, SK Kulkarni - European journal of pharmacology, 2008 - Elsevier
Glia, particularly astrocytes and microglia, are known to play an important role in central
sensitization and are strongly implicated in the exaggerated pain states. In the present study …

β‐Cyclodextrin‐complexed ()‐linalool produces antinociceptive effect superior to that of ()‐linalool in experimental pain protocols

LJ Quintans‐Júnior, RSS Barreto… - Basic & clinical …, 2013 - Wiley Online Library
Abstract Many plants produce (−)‐linalool, a plant‐derived monoterpene alcohol, including
members of the L amiaceae (mints) and L auraceae family (laurels, cinnamon, rosewood) …

Antibacterial mechanisms and efficacy of sarecycline in animal models of infection and inflammation

CG Bunick, J Keri, SK Tanaka, N Furey, G Damiani… - Antibiotics, 2021 - mdpi.com
Prolonged broad-spectrum antibiotic use is more likely to induce bacterial resistance and
dysbiosis of skin and gut microflora. First and second-generation tetracycline-class …

Development of a new polypropylene‐based suture: plasma grafting, surface treatment, characterization, and biocompatibility studies

S Saxena, AR Ray, A Kapil… - Macromolecular …, 2011 - Wiley Online Library
Polypropylene sutures (PP) are already used in surgery. Because microbial infection leads
to complications, we developed antimicrobial PP suture by plasma‐induced graft …

Anti-inflammatory properties of doxycycline and minocycline in experimental models: an in vivo and in vitro comparative study

LM Leite, AGG Carvalho, PLF Tavares Ferreira… - …, 2011 - Springer
Abstract Aims and methods Minocycline (Mino) and doxycycline (Dox) are second
generation tetracyclines known to present several other effects, which are independent from …