A critical overview of targeted therapies for glioblastoma

KK Jain - Frontiers in oncology, 2018 - frontiersin.org
Over the past century, treatment of malignant tumors of the brain has remained a challenge.
Refinements in neurosurgical techniques, discovery of powerful chemotherapeutic agents …

Adhesion G protein-coupled receptors: structure, signaling, physiology, and pathophysiology

T Lala, RA Hall - Physiological Reviews, 2022 - journals.physiology.org
Adhesion G protein-coupled receptors: structure, signaling, physiology, and
pathophysiology Page 1 REVIEW ARTICLE ADHESION G PROTEIN-COUPLED …

[HTML][HTML] A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis

M Masiero, FC Simões, HD Han, C Snell, T Peterkin… - Cancer cell, 2013 - cell.com
Limited clinical benefits derived from anti-VEGF therapy have driven the identification of new
targets involved in tumor angiogenesis. Here, we report an integrative meta-analysis to …

[图书][B] The handbook of biomarkers

KK Jain, KK Jain - 2010 - Springer
There are several definitions of biomarkers. A biomarker is a characteristic that can be
objectively measured and evaluated as an indicator of a physiological as well as a …

Immunologically modified MnFe2O4 nanoparticles to synergize photothermal therapy and immunotherapy for cancer treatment

B Zhou, Q Wu, M Wang, A Hoover, X Wang… - Chemical Engineering …, 2020 - Elsevier
Immunotherapy has been a promising candidate for cancer treatment. The combination of
photothermal therapy (PTT) and immunotherapy have shown to cause tumor ablation and …

Adhesion G protein–coupled receptors as drug targets

RH Purcell, RA Hall - Annual review of pharmacology and …, 2018 - annualreviews.org
The adhesion G protein–coupled receptors (aGPCRs) are an evolutionarily ancient family of
receptors that play key roles in many different physiological processes. These receptors are …

Liquid biopsy: creating opportunities in brain space

R Trivedi, KP Bhat - British journal of cancer, 2023 - nature.com
In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …

Advances in antibody-based drugs and their delivery through the blood-brain barrier for targeted therapy and immunotherapy of gliomas

X Huang, S Shi, H Wang, T Zhao, Y Wang… - International …, 2023 - Elsevier
Gliomas are highly invasive and are the most common type of primary malignant brain
tumor. The routine treatments for glioma include surgical resection, radiotherapy, and …

A 19-Gene expression signature as a predictor of survival in colorectal cancer

NA Abdul Aziz, NM Mokhtar, R Harun… - BMC medical …, 2016 - Springer
Background Histopathological assessment has a low potential to predict clinical outcome in
patients with the same stage of colorectal cancer. More specific and sensitive biomarkers to …

Emerging biomarkers in glioblastoma

MG McNamara, S Sahebjam, WP Mason - Cancers, 2013 - mdpi.com
Glioblastoma, the most common primary brain tumor, has few available therapies providing
significant improvement in survival. Molecular signatures associated with tumor …