The clinical handling of chronic virus infections remains a challenge. Here we describe
recent progress in the understanding of virus-host interaction dynamics. Based on the …

Mathematical models with time delays are widely used to analyze the mechanisms of the
immune response to virus infections and predict various therapeutic effects. Using the …

A concept of optimal disturbances of periodic solutions for a system of time-delay differential
equations is defined. An algorithm for computing the optimal disturbances is proposed and …

The paper is focused on the dependence of optimal disturbances of stable periodic solutions
of time-delay systems on phases of such solutions. The results of numerical experiments …

Novel fast algorithms for computing the maximum amplification of the norm of solution and
optimal disturbances for delay systems are proposed and justified. The proposed algorithms …

Optimal disturbances of the periodic solution of the hepatitis B dynamics model
corresponding to the chronic recurrent form of the disease are found. The dependence of the …

Optimal disturbances of a number of typical stationary solutions of the hepatitis B virus
infection dynamics model have been found. Specifically optimal disturbances have been …

This work is devoted to the technology developed by the authors that allows one for fixed
values of parameters and tracing by parameters to calculate stationary solutions of systems …

This work is devoted to the technology developed by the authors that allows one for fixed
values of parameters and tracing by parameters to calculate stationary solutions of systems …

Данная работа посвящена разработанной авторами технологии вычисления при
фиксированных значениях параметров и трассирования по параметрам стационарных …