Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease

SM Ishtiaq, H Rashid, Z Hussain, MI Arshad… - Reviews in Endocrine …, 2019 - Springer
Adiponectin, a soluble adipocytokine, plays an important role in the functioning of adipose
tissue and in the regulation of inflammation, particularly hepatic inflammation. The …

Pectolinarigenin ameliorates acetaminophen-induced acute liver injury via attenuating oxidative stress and inflammatory response in Nrf2 and PPARa dependent …

Q Li, W Zhang, N Cheng, Y Zhu, H Li, S Zhang, W Guo… - Phytomedicine, 2023 - Elsevier
Abstract Background Cirsii Japonici Herba Carbonisata (Dajitan in Chinese) has been used
to treat liver disorders in Asian countries. Pectolinarigenin (PEC), an abundant constituent in …

Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review

ME Mullins, LH Yeager, WE Freeman - Clinical Toxicology, 2020 - Taylor & Francis
Background Paracetamol (acetaminophen) remains a leading cause of poisoning in Europe,
North America, and Australia. For over four decades, acetylcysteine has been the antidote of …

The Essential Oils and Eucalyptol From Artemisia vulgaris L. Prevent Acetaminophen-Induced Liver Injury by Activating Nrf2–Keap1 and Enhancing APAP Clearance …

Z Jiang, X Guo, K Zhang, G Sekaran, B Cao… - Frontiers in …, 2019 - frontiersin.org
Artemisia has long been used in traditional medicine and as a food source for different
functions in eastern Asia. Artemisia vulgaris L.(AV) is a species of the genus Artemisia …

Protective role of Chlorella vulgaris with Thiamine against Paracetamol induced toxic effects on haematological, biochemical, oxidative stress parameters and …

AAE Latif, DH Assar, EM Elkaw, HA Hamza… - Scientific Reports, 2021 - nature.com
Paracetamol is extensively consumed as an analgesic and antipyretic drug, but at a high
dose level, it leads to deleterious side effects, such as hepatic and nephrotoxicity. This …

Acetaminophen aggravates fat accumulation in NAFLD by inhibiting autophagy via the AMPK/mTOR pathway

C Shi, W Xue, B Han, F Yang, Y Yin, C Hu - European journal of …, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease which
affects millions of people worldwide. Acetaminophen (APAP) overdose is the leading cause …

[HTML][HTML] Protective effect of inulin on methotrexate-induced liver toxicity in mice

H Kalantari, N Asadmasjedi, M reza Abyaz… - Biomedicine & …, 2019 - Elsevier
Methotrexate (MTX) is an effectively used drug in the treatment of cancer and inflammatory
diseases but, its use is related with hepatotoxicity. Inulin with antioxidant properties has …

[HTML][HTML] Effect of gemfibrozil on cardiotoxicity induced by doxorubicin in male experimental rats

H Haybar, M Goudarzi, S Mehrzadi… - Biomedicine & …, 2019 - Elsevier
Cardiotoxicity is an adverse effect of the anticancer drug doxorubicin (DOX). Gemfibrozil
(GEM) is a lipid-lowering drug with a number of biological properties such as anti …

Gemfibrozil, a lipid‐lowering drug, improves hepatorenal damages in a mouse model of aging

E Hakimizadeh, S Tadayon… - Fundamental & …, 2023 - Wiley Online Library
Gemfibrozil (GFZ) is a medication of the fibrate category with agonistic effects on peroxisome
proliferator‐activated receptor‐α (PPAR‐α) and is effective for hypertriglyceridemia and …

[HTML][HTML] Novel insights on toxicology of ochratoxin A contaminated diets to skin: Residues, mucus disruption and barrier impairment in teleost model grass carp …

P Zhao, X Liu, WD Jiang, P Wu, Y Liu, HM Ren… - Ecotoxicology and …, 2023 - Elsevier
Ochratoxin A (OTA), a notorious pollutant widely present worldwide, seriously pollutes
aquafeeds. This paper aims to explore the toxicity effects of OTA by the way of diet on the …