[HTML][HTML] Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities

KD Davis, N Aghaeepour, AH Ahn, MS Angst… - Nature Reviews …, 2020 - nature.com
Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

[HTML][HTML] Biomarkers in psychiatry: concept, definition, types and relevance to the clinical reality

MS García-Gutiérrez, F Navarrete, F Sala… - Frontiers in …, 2020 - frontiersin.org
During the last years, an extraordinary effort has been made to identify biomarkers as
potential tools for improving prevention, diagnosis, drug response and drug development in …

TheMarker: a comprehensive database of therapeutic biomarkers

Y Zhang, Y Zhou, Y Zhou, X Yu, X Shen… - Nucleic Acids …, 2024 - academic.oup.com
Distinct from the traditional diagnostic/prognostic biomarker (adopted as the indicator of
disease state/process), the therapeutic biomarker (ThMAR) has emerged to be very crucial …

[HTML][HTML] Machine learning models for the identification of prognostic and predictive cancer biomarkers: a systematic review

Q Al-Tashi, MB Saad, A Muneer, R Qureshi… - International journal of …, 2023 - mdpi.com
The identification of biomarkers plays a crucial role in personalized medicine, both in the
clinical and research settings. However, the contrast between predictive and prognostic …

Necrotizing enterocolitis

J Duchon, ME Barbian… - Clinics in …, 2021 - perinatology.theclinics.com
Necrotizing enterocolitis (NEC) is a devastating intestinal disorder characterized by
intestinal inflammation and necrosis. 1 This disease is one of the most common …

A systematic review on biomarker identification for cancer diagnosis and prognosis in multi-omics: from computational needs to machine learning and deep learning

A Dhillon, A Singh, VK Bhalla - Archives of Computational Methods in …, 2023 - Springer
Biomarkers, also known as biological markers, are substances like transcripts,
deoxyribonucleic acid (DNA), genes, proteins, and metabolites that indicate whether a …

[HTML][HTML] High-grade glioma treatment response monitoring biomarkers: a position statement on the evidence supporting the use of advanced MRI techniques in the …

OM Henriksen, M del Mar Álvarez-Torres… - Frontiers in …, 2022 - frontiersin.org
Objective Summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods …

[HTML][HTML] Machine learning and glioma imaging biomarkers

TC Booth, M Williams, A Luis, J Cardoso, K Ashkan… - Clinical radiology, 2020 - Elsevier
AIM To review how machine learning (ML) is applied to imaging biomarkers in neuro-
oncology, in particular for diagnosis, prognosis, and treatment response monitoring …

[HTML][HTML] Imaging biomarkers for clinical applications in neuro-oncology: current status and future perspectives

FY Chiu, Y Yen - Biomarker Research, 2023 - Springer
Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …

[HTML][HTML] Impact of mobile health and medical applications on clinical practice in gastroenterology

S Kernebeck, TS Busse, MD Böttcher… - World journal of …, 2020 - ncbi.nlm.nih.gov
Mobile health apps (MHAs) and medical apps (MAs) are becoming increasingly popular as
digital interventions in a wide range of health-related applications in almost all sectors of …