AGA clinical practice update on de-prescribing of proton pump inhibitors: expert review

LE Targownik, DA Fisher, SD Saini - Gastroenterology, 2022 - Elsevier
Description Proton pump inhibitors (PPIs) are among the most commonly used medications
in the world. Developed for the treatment and prevention of acid-mediated upper …

[HTML][HTML] Proton pump inhibitor use: systematic review of global trends and practices

LGT Shanika, A Reynolds, S Pattison… - European Journal of …, 2023 - Springer
Abstract Purpose Proton pump inhibitors (PPIs) reduce acid secretion in the stomach and
rank as one of the most widely used acid-suppressing medicines globally. While PPIs are …

Proton pump inhibitor use and risk of serious infections in young children

M Lassalle, M Zureik, R Dray-Spira - JAMA pediatrics, 2023 - jamanetwork.com
Importance Proton pump inhibitor (PPI) use may lead to infections through alteration of the
microbiota or direct action on the immune system. However, only a few studies were …

[HTML][HTML] Evolution of the consumption trend of proton pump inhibitors in the Lleida Health Region between 2002 and 2015

F Torres-Bondia, J de Batlle, L Galván, M Buti… - BMC Public Health, 2022 - Springer
Abstract Background Proton pump inhibitors (PPIs) are one of the most commonly
prescribed pharmacological groups. Their high prevalence and duration of use are of …

[HTML][HTML] Do proton pump inhibitors alter the response to immune checkpoint inhibitors in cancer patients? A meta-analysis

S Lopes, L Pabst, A Dory, M Klotz, B Gourieux… - Frontiers in …, 2023 - frontiersin.org
Introduction Gut microbiota can significantly affect the effectiveness of immune checkpoint
inhibitors (ICIs) in cancer patients. Recently, antibiotics were shown to decrease survival …

Proton pump inhibitor utilisation and potentially inappropriate prescribing analysis: insights from a single-centred retrospective study

Y Liu, X Zhu, R Li, J Zhang, F Zhang - BMJ open, 2020 - bmjopen.bmj.com
Objectives This study aimed to characterise the prescribing patterns and evaluate the
appropriateness of the prescribed proton pump inhibitors (PPIs) in adult patients via a …

Potentially inappropriate proton-pump inhibitor prescription in the general population: a claims-based retrospective time trend analysis

L Muheim, A Signorell, S Markun… - Therapeutic …, 2021 - journals.sagepub.com
Background: Proton-pump inhibitors (PPI) are among the most prescribed drugs worldwide,
and a large body of evidence raises concerns about their inappropriate use. Previous …

Pediatric prescriptions of proton pump inhibitors in France (2009-2019): a time-series analysis of trends and practice guidelines impact

S Yang, NTH Trinh, M Chalumeau, F Kaguelidou… - The Journal of …, 2022 - Elsevier
Objective To describe the ambulatory proton pump inhibitor (PPI) prescription in French
children, its trends, and the impact of French (2014) and international (2018) clinical …

[HTML][HTML] Who gets prescriptions for proton pump inhibitors and why? A drug-utilization study with claims data in Bavaria, Germany, 2010–2018

IM Rückert-Eheberg, M Nolde, N Ahn… - European journal of …, 2022 - Springer
Abstract Purpose The German annual drug prescription-report has indicated overuse of
proton pump inhibitors (PPIs) for many years; however, little was known about the …

[HTML][HTML] Proton pump inhibitors and cancer: current state of play

M Bridoux, N Simon, A Turpin - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Proton pump inhibitors (PPIs) are one of the most widely used drugs worldwide
and are overprescribed in patients with cancer; there is increasing evidence of their effects …