Targeting signaling pathways in prostate cancer: mechanisms and clinical trials

Y He, W Xu, YT Xiao, H Huang, D Gu… - Signal transduction and …, 2022 - nature.com
Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …

Testosterone replacement therapy

A Barbonetti, S D'Andrea, S Francavilla - Andrology, 2020 - Wiley Online Library
Background The aim of testosterone replacement therapy (TRT) is to improve symptoms and
signs of testosterone deficiency including decreased libido, erectile dysfunction, depressed …

Testosterone therapy in men with hypogonadism: an endocrine society clinical practice guideline

S Bhasin, JP Brito, GR Cunningham… - The Journal of …, 2018 - academic.oup.com
Abstract Objective To update the “Testosterone Therapy in Men With Androgen Deficiency
Syndromes” guideline published in 2010. Participants The participants include an Endocrine …

NCCN Guidelines® Insights: prostate cancer early detection, version 1.2023: featured updates to the NCCN guidelines

KA Moses, PC Sprenkle, C Bahler, G Box… - Journal of the National …, 2023 - jnccn.org
The NCCN Guidelines for Prostate Cancer Early Detection provide recommendations for
individuals with a prostate who opt to participate in an early detection program after …

[PDF][PDF] 中国前列腺癌筛查与早诊早治指南(2022, 北京).

赫捷, 陈万青, 李霓, 曹巍, 叶定伟, 马建辉… - Chinese Journal of …, 2022 - jhxrmyy.com
前列腺癌是好发于老年男性的生殖系统恶性肿瘤. 前列腺癌高风险人群筛查与患者的早诊早治对
提高前列腺癌治愈率至关重要. 制定符合中国国情的前列腺癌筛查与早诊早治指南 …

Recent advances and future perspectives in the therapeutics of prostate cancer

GL Varaprasad, VK Gupta, K Prasad, E Kim… - … Hematology & Oncology, 2023 - Springer
Prostate cancer (PC) is one of the most common cancers in males and the fifth leading
reason of death. Age, ethnicity, family history, and genetic defects are major factors that …

Prostate Cancer Foundation screening guidelines for Black men in the United States

IP Garraway, SV Carlsson, YA Nyame, JL Vassy… - NEJM …, 2024 - evidence.nejm.org
Abstract Background In the United States, Black men are at highest risk for being diagnosed
with and dying from prostate cancer. Given this disparity, we examined relevant data to …

Value of handcrafted and deep radiomic features towards training robust machine learning classifiers for prediction of prostate cancer disease aggressiveness

A Rodrigues, N Rodrigues, J Santinha… - Scientific Reports, 2023 - nature.com
There is a growing piece of evidence that artificial intelligence may be helpful in the entire
prostate cancer disease continuum. However, building machine learning algorithms robust …

Digital rectal examination is not a useful screening test for prostate cancer

A Krilaviciute, N Becker, J Lakes, JP Radtke… - European Urology …, 2023 - Elsevier
Background Annual digital rectal examination (DRE) is recommended as a stand-alone
screening test for prostate cancer (PCa) in Germany for 45+ yr olds. DRE diagnostic …

Prostate specific antigen density as a predictor of clinically significant prostate cancer when the prostate specific antigen is in the diagnostic gray zone: defining the …

A Aminsharifi, L Howard, Y Wu, A De Hoedt… - The Journal of …, 2018 - auajournals.org
Purpose: We assessed the predictive value of prostate specific antigen density to detect
clinically significant prostate cancer, defined as prostate cancer grade group 2 or greater, in …