The forgotten lipids: triglycerides, remnant cholesterol, and atherosclerotic cardiovascular disease risk

PB Sandesara, SS Virani, S Fazio… - Endocrine …, 2019 - academic.oup.com
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death
worldwide. Low-density lipoprotein cholesterol (LDL-C) is a well-established mediator of …

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus …

HN Ginsberg, CJ Packard, MJ Chapman… - European heart …, 2021 - academic.oup.com
Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …

From high-density lipoprotein cholesterol to measurements of function: prospects for the development of tests for high-density lipoprotein functionality in …

FM Sacks, MK Jensen - Arteriosclerosis, thrombosis, and vascular …, 2018 - Am Heart Assoc
The evidence is strong that biological functions contained in high-density lipoproteins (HDL)
are antiatherogenic. These functions may track with HDL cholesterol or apolipoprotein A1 …

Quantifying atherogenic lipoproteins: current and future challenges in the era of personalized medicine and very low concentrations of LDL cholesterol. A consensus …

MR Langlois, MJ Chapman, C Cobbaert… - Clinical …, 2018 - academic.oup.com
Abstract BACKGROUND The European Atherosclerosis Society–European Federation of
Clinical Chemistry and Laboratory Medicine Consensus Panel aims to provide …

Remnant lipoprotein cholesterol and incident coronary heart disease: the Jackson Heart and Framingham Offspring Cohort Studies

PH Joshi, AA Khokhar, JM Massaro… - Journal of the …, 2016 - Am Heart Assoc
Background Remnant lipoproteins (RLPs), the triglyceride‐enriched precursors to low‐
density lipoprotein, are an emerging risk factor for coronary heart disease (CHD). We sought …

Profound reductions in first and total cardiovascular events with icosapent ethyl in the REDUCE-IT trial: why these results usher in a new era in dyslipidaemia …

WE Boden, DL Bhatt, PP Toth, KK Ray… - European heart …, 2020 - academic.oup.com
The aims of this clinical review are to:(i) highlight the importance of elevated baseline
triglycerides (TG) in the setting of well-controlled low-density lipoprotein cholesterol (LDL-C) …

Remnant lipoproteins

A Varbo, BG Nordestgaard - Current opinion in lipidology, 2017 - journals.lww.com
Remnant lipoproteins : Current Opinion in Lipidology Remnant lipoproteins : Current
Opinion in Lipidology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet …

Protein-defined subspecies of HDLs (high-density lipoproteins) and differential risk of coronary heart disease in 4 prospective studies

FM Sacks, L Liang, JD Furtado, T Cai… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: HDL (high-density lipoprotein) contains functional proteins that define single
subspecies, each comprising 1% to 12% of the total HDL. We studied the differential …

Associations between high-density lipoprotein particles and ischemic events by vascular domain, sex, and ethnicity: a pooled cohort analysis

K Singh, A Chandra, T Sperry, PH Joshi, A Khera… - Circulation, 2020 - Am Heart Assoc
Background: High-density lipoprotein (HDL) cholesterol concentration (HDL-C) is an
established atheroprotective marker, in particular for coronary artery disease; however, HDL …

[HTML][HTML] Association of elevated triglycerides with increased cardiovascular risk and direct costs in statin-treated patients

PP Toth, S Philip, M Hull, C Granowitz - Mayo Clinic Proceedings, 2019 - Elsevier
Objective To retrospectively investigate the real-world impact of elevated triglyceride (TG)
levels on cardiovascular (CV) outcomes, medical resource utilization, and medical costs …