Analysis of DNA methylation in cancer: location revisited
A Koch, SC Joosten, Z Feng, TC de Ruijter… - Nature reviews Clinical …, 2018 - nature.com
Abstract Changes in DNA methylation in cancer have been heralded as promising targets
for the development of powerful diagnostic, prognostic, and predictive biomarkers. Despite …
for the development of powerful diagnostic, prognostic, and predictive biomarkers. Despite …
Epigenetic regulation of gene expression in cancer: techniques, resources and analysis
LT Kagohara, GL Stein-O'Brien, D Kelley… - Briefings in …, 2018 - academic.oup.com
Cancer is a complex disease, driven by aberrant activity in numerous signaling pathways in
even individual malignant cells. Epigenetic changes are critical mediators of these functional …
even individual malignant cells. Epigenetic changes are critical mediators of these functional …
MethSurv: a web tool to perform multivariable survival analysis using DNA methylation data
V Modhukur, T Iljasenko, T Metsalu, K Lokk… - …, 2018 - Future Medicine
Aim: To develop a web tool for survival analysis based on CpG methylation patterns.
Materials & methods: We utilized methylome data from 'The Cancer Genome Atlas' and used …
Materials & methods: We utilized methylome data from 'The Cancer Genome Atlas' and used …
[PDF][PDF] OncoLnc: linking TCGA survival data to mRNAs, miRNAs, and lncRNAs
J Anaya - PeerJ Computer Science, 2016 - peerj.com
OncoLnc is a tool for interactively exploring survival correlations, and for downloading
clinical data coupled to expression data for mRNAs, miRNAs, or long noncoding RNAs …
clinical data coupled to expression data for mRNAs, miRNAs, or long noncoding RNAs …
MEXPRESS update 2019
The recent growth in the number of publicly available cancer omics databases has been
accompanied by the development of various tools that allow researchers to visually explore …
accompanied by the development of various tools that allow researchers to visually explore …
[HTML][HTML] CDKN2A-mediated molecular subtypes characterize the hallmarks of tumor microenvironment and guide precision medicine in triple-negative breast cancer
T Cheng, Y Wu, Z Liu, Y Yu, S Sun, M Guo… - Frontiers in …, 2022 - frontiersin.org
Currently, breast cancer (BRCA) has become the most common cancer in the world, whose
pathological mechanism is complex. Among its subtypes, triple-negative breast cancer …
pathological mechanism is complex. Among its subtypes, triple-negative breast cancer …
[HTML][HTML] Identification of hub genes in prostate cancer using robust rank aggregation and weighted gene co-expression network analysis
The pathogenic mechanisms of prostate cancer (PCa) remain to be defined. In this study, we
utilized the Robust Rank Aggregation (RRA) method to integrate 10 eligible PCa microarray …
utilized the Robust Rank Aggregation (RRA) method to integrate 10 eligible PCa microarray …
[HTML][HTML] Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma
J Wei, Z Xu, X Chen, X Wang… - Molecular …, 2020 - spandidos-publications.com
The gasdermin (GSDM) superfamily has been demonstrated to consist of several important
molecules that modulate multifunctional signal processes, such as cell pyroptosis. In this …
molecules that modulate multifunctional signal processes, such as cell pyroptosis. In this …
[HTML][HTML] A pan-cancer analysis of GINS complex subunit 4 to identify its potential role as a biomarker in multiple human cancers
M Usman, MK Okla, HM Asif… - American Journal of …, 2022 - ncbi.nlm.nih.gov
This study was initiated to explore the expression variation, clinical significance, and
biological importance of the GINS complex subunit 4 (GINS4) in different human cancers as …
biological importance of the GINS complex subunit 4 (GINS4) in different human cancers as …
[HTML][HTML] Correlation of MKI67 with prognosis, immune infiltration, and T cell exhaustion in hepatocellular carcinoma
S Wu, P Liao, L Yan, Q Zhao, Z Xie, J Dong… - BMC gastroenterology, 2021 - Springer
Background MKI67 plays a vital role in the tumour microenvironment (TME) and congenital
immunity. The present work focuses on exploring the prognosis prediction performance of …
immunity. The present work focuses on exploring the prognosis prediction performance of …