Genetics of age-related macular degeneration (AMD)
MM DeAngelis, LA Owen, MA Morrison… - Human molecular …, 2017 - academic.oup.com
Age-related macular degeneration (AMD) is a progressive blinding disease and represents
the leading cause of visual impairment in the aging population. AMD affects central vision …
the leading cause of visual impairment in the aging population. AMD affects central vision …
[HTML][HTML] Animal models of ocular angiogenesis: from development to pathologies
Pathological angiogenesis in the eye is an important feature in the pathophysiology of many
vision-threatening diseases, including retinopathy of prematurity, diabetic retinopathy, and …
vision-threatening diseases, including retinopathy of prematurity, diabetic retinopathy, and …
[WITHDRAWN] retinal vasculature in development and diseases
This article was withdrawn on October 15, 2020, at the request of the journal editors, with
agreement from the authors, owing to a substantial amount of unattributed or improperly …
agreement from the authors, owing to a substantial amount of unattributed or improperly …
Microglia inhibit photoreceptor cell death and regulate immune cell infiltration in response to retinal detachment
Y Okunuki, R Mukai, EA Pearsall… - Proceedings of the …, 2018 - National Acad Sciences
Retinal detachment (RD) is a sight-threatening complication common in many highly
prevalent retinal disorders. RD rapidly leads to photoreceptor cell death beginning within 12 …
prevalent retinal disorders. RD rapidly leads to photoreceptor cell death beginning within 12 …
Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics
Tissue microarchitecture and mechanics are important in development and pathologies of
the Central Nervous System (CNS); however, their coordinating mechanisms are unclear …
the Central Nervous System (CNS); however, their coordinating mechanisms are unclear …
Interpretation of OCT and OCTA images from a histological approach: clinical and experimental implications
Optical coherence tomography (OCT) and OCT angiography (OCTA) have been a
technological breakthrough in the diagnosis, treatment, and follow-up of many retinal …
technological breakthrough in the diagnosis, treatment, and follow-up of many retinal …
Sirt1: a guardian of the development of diabetic retinopathy
M Mishra, AJ Duraisamy, RA Kowluru - Diabetes, 2018 - Am Diabetes Assoc
Diabetic retinopathy is a multifactorial disease, and the exact mechanism of its pathogenesis
remains obscure. Sirtuin 1 (Sirt1), a multifunctional deacetylase, is implicated in the …
remains obscure. Sirtuin 1 (Sirt1), a multifunctional deacetylase, is implicated in the …
Delineating effects of angiopoietin-2 inhibition on vascular permeability and inflammation in models of retinal neovascularization and ischemia/reperfusion
J Canonica, R Foxton, MG Garrido, CM Lin… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Clinical trials demonstrated that co-targeting angiopoietin-2 (Ang-2) and
vascular endothelial growth factor (VEGF-A) with faricimab controls anatomic outcomes and …
vascular endothelial growth factor (VEGF-A) with faricimab controls anatomic outcomes and …
Assessment of Inner Blood–Retinal Barrier: Animal Models and Methods
Proper functioning of the neural retina relies on the unique retinal environment regulated by
the blood–retinal barrier (BRB), which restricts the passage of solutes, fluids, and toxic …
the blood–retinal barrier (BRB), which restricts the passage of solutes, fluids, and toxic …
Noninvasive delivery of self-regenerating cerium oxide nanoparticles to modulate oxidative stress in the retina
CS Shin, RA Veettil, TS Sakthivel… - ACS Applied Bio …, 2022 - ACS Publications
Diseases affecting the retina, such as age-related macular degeneration (AMD), diabetic
retinopathy, macular edema, and retinal vein occlusions, are currently treated by the …
retinopathy, macular edema, and retinal vein occlusions, are currently treated by the …