Bacterial transformation: distribution, shared mechanisms and divergent control

C Johnston, B Martin, G Fichant, P Polard… - Nature Reviews …, 2014 - nature.com
Natural bacterial transformation involves the internalization and chromosomal integration of
DNA and has now been documented in∼ 80 species. Recent advances have established …

Biosynthesis and function of modified bases in bacteria and their viruses

P Weigele, EA Raleigh - Chemical reviews, 2016 - ACS Publications
Naturally occurring modification of the canonical A, G, C, and T bases can be found in the
DNA of cellular organisms and viruses from all domains of life. Bacterial viruses …

[HTML][HTML] Horizontal gene transfer: essentiality and evolvability in prokaryotes, and roles in evolutionary transitions

EV Koonin - F1000Research, 2016 - ncbi.nlm.nih.gov
The wide spread of gene exchange and loss in the prokaryotic world has prompted the
concept of 'lateral genomics' to the point of an outright denial of the relevance of …

Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification

LM Iyer, D Zhang, L Aravind - Bioessays, 2016 - Wiley Online Library
While N6‐methyladenosine (m6A) is a well‐known epigenetic modification in bacterial DNA,
it remained largely unstudied in eukaryotes. Recent studies have brought to fore its potential …

A visual review of the human pathogen Streptococcus pneumoniae

DH Engholm, M Kilian, DS Goodsell… - FEMS microbiology …, 2017 - academic.oup.com
Being the principal causative agent of bacterial pneumonia, otitis media, meningitis and
septicemia, the bacterium Streptococcus pneumoniae is a major global health problem. To …

[HTML][HTML] Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae

J Li, JW Li, Z Feng, J Wang, H An, Y Liu, Y Wang… - PLoS …, 2016 - journals.plos.org
DNA methylation is an important epigenetic mechanism for phenotypic diversification in all
forms of life. We previously described remarkable cell-to-cell heterogeneity in epigenetic …

Regulation of competence for natural transformation in streptococci

L Fontaine, A Wahl, M Fléchard, J Mignolet… - Infection, Genetics and …, 2015 - Elsevier
Natural DNA transformation is a lateral gene transfer mechanism during which bacteria take
up naked DNA from their environment and stably integrate it in their genome. The proteins …

Phase-variable methylation and epigenetic regulation by type I restriction–modification systems

M De Ste Croix, I Vacca, MJ Kwun… - FEMS microbiology …, 2017 - academic.oup.com
Epigenetic modifications in bacteria, such as DNA methylation, have been shown to affect
gene regulation, thereby generating cells that are isogenic but with distinctly different …

Coinfinder: detecting significant associations and dissociations in pangenomes

FJ Whelan, M Rusilowicz… - Microbial …, 2020 - microbiologyresearch.org
The accessory genes of prokaryote and eukaryote pangenomes accumulate by horizontal
gene transfer, differential gene loss, and the effects of selection and drift. We have …

[HTML][HTML] Natural Competence Is Common among Clinical Isolates of Veillonella parvula and Is Useful for Genetic Manipulation of This Key Member of the Oral …

S Knapp, C Brodal, J Peterson, F Qi, J Kreth… - Frontiers in Cellular …, 2017 - frontiersin.org
The six Veillonella species found in the human oral cavity are among the most abundant
members of the oral flora, occurring in both supra-and subgingival dental plaque as well as …