Clinical features, immunopathogenesis, and therapeutic strategies in vitiligo

Y Wang, S Li, C Li - Clinical Reviews in Allergy & Immunology, 2021 - Springer
Vitiligo is an autoimmune disease of the skin characterized by epidermal melanocyte loss
resulting in white patches, with an approximate prevalence of 0.5–2% worldwide. Several …

UVB phototherapy in the treatment of vitiligo: State of the art and clinical perspectives

R Bouceiro Mendes, M Alpalhão… - Photodermatology …, 2022 - Wiley Online Library
Vitiligo is a chronic pigmentary skin disorder that results in white, hypopigmented macules
and patches. It causes a considerable psychological and emotional burden on the affected …

Safety Data in Patients with Autoimmune Diseases during Treatment with High Doses of Vitamin D3 According to the “Coimbra Protocol”

U Amon, R Yaguboglu, M Ennis, MF Holick, J Amon - Nutrients, 2022 - mdpi.com
Background: In 2013, the group of Cicero Coimbra, Brazil, reported the clinical efficacy of
high doses of vitamin D3 in patients suffering from autoimmune skin disorders (“Coimbra …

Calcium controlled NFATc1 activation enhances suppressive capacity of regulatory T cells isolated from generalized vitiligo patients

PS Giri, AH Bharti, R Begum, M Dwivedi - Immunology, 2022 - Wiley Online Library
NFATs and FOXP3 are linked with impaired regulatory T‐cells (Tregs) in generalized vitiligo
(GV). To elucidate calcium mediated NFATc1 signalling pathway and its effect on Treg …

Testing the empirical integration of threat-deprivation and harshness-unpredictability dimensional models of adversity

M Usacheva, D Choe, S Liu, S Timmer… - Development and …, 2022 - cambridge.org
Recent dimensional models of adversity informed by a neurobiological deficit framework
highlights threat and deprivation as core dimensions, whereas models informed by an …

Decreased suppression of CD8+ and CD4+ T cells by peripheral regulatory T cells in generalized vitiligo due to reduced NFATC1 and FOXP3 proteins

PS Giri, M Dwivedi, R Begum - Experimental Dermatology, 2020 - Wiley Online Library
Regulatory T cells (Tregs) are involved in the suppression of activated T cells in generalized
vitiligo (GV). The study was aimed to investigate Tregs functional defects in Treg: CD8+ and …

Enzyme/nanocopper hybrid nanozymes: Modulating enzyme-like activity by the protein structure for biosensing and tumor catalytic therapy

N Losada-Garcia, A Jimenez-Alesanco… - … Applied Materials & …, 2021 - ACS Publications
Artificial enzymes with modulated enzyme-mimicking activities of natural systems represent
a challenge in catalytic applications. Here, we show the creation of artificial Cu …

The role of pragmatics in the definition of evidentiality

H Bergqvist, K Grzech - STUF-Language Typology and Universals, 2023 - degruyter.com
This paper argues that a definition of evidentiality as a linguistic notion should be based on
the pragmatic properties of evidential forms and their distribution in spoken discourse. The …

Support for increased cardiovascular risk in non‐segmental vitiligo among Egyptians: A hospital‐based, case–control study

Y Azzazi, WZ Mostafa, KS Sayed… - Pigment Cell & …, 2021 - Wiley Online Library
Background Data have been accumulating in the past few years that identify vitiligo as a
disorder with systemic implications. Results and methods In this hospital‐based, cross …

The Role of TRM Cells in the Pathogenesis of Vitiligo—A Review of the Current State-Of-The-Art

A Frączek, A Owczarczyk-Saczonek… - International Journal of …, 2020 - mdpi.com
Vitiligo is the most common hypopigmentation disease affecting both the skin and mucous
membranes. The pathogenesis of this disorder is complex and involves the influence of …