Efficacy and tolerability of pharmacological treatments for insomnia in adults: A systematic review and network meta-analysis

JL Yue, XW Chang, JW Zheng, L Shi, YJ Xiang… - Sleep medicine …, 2023 - Elsevier
Insomnia is one of the most common and burdensome disorders in adults. We compared
and ranked insomnia medication on the basis of their efficacy and tolerability. We performed …

Insomnia symptoms as risk factor for somatic disorders: An umbrella review of systematic reviews and meta‐analyses

F Benz, D Meneo, C Baglioni… - Journal of sleep …, 2023 - Wiley Online Library
The objective of this umbrella review is to present a comprehensive summary of systematic
reviews and meta‐analyses on the longitudinal association between insomnia and the risk …

Comorbid insomnia and sleep apnoea is associated with all-cause mortality

B Lechat, S Appleton, YA Melaku… - European …, 2022 - Eur Respiratory Soc
Background Increased mortality has been reported in people with insomnia and in those
with obstructive sleep apnoea (OSA). However, these conditions commonly co-occur and …

Adherence to a healthy sleep pattern is associated with lower risks of all‐cause, cardiovascular and cancer‐specific mortality

T Zhou, Y Yuan, Q Xue, X Li, M Wang… - Journal of internal …, 2022 - Wiley Online Library
Background Individual unhealthy sleep behaviours have been associated with increased
risks of all‐cause mortality and deaths due to cardiovascular disease (CVD) or cancer. The …

[HTML][HTML] Efficacy and safety of Ashwagandha (Withania somnifera) root extract in insomnia and anxiety: a double-blind, randomized, placebo-controlled study

D Langade, S Kanchi, J Salve, K Debnath… - Cureus, 2019 - ncbi.nlm.nih.gov
Objective To determine the efficacy and safety of Ashwagandha root extract in patients with
insomnia and anxiety. Methods This was a randomized, double-blind, placebo-controlled …

Insomnia and multiple health outcomes: umbrella review of meta-analyses of prospective cohort studies

TT Wu, YL Zou, KD Xu, XR Jiang, MM Zhou, SB Zhang… - Public Health, 2023 - Elsevier
Objectives To evaluate existing evidence of prospective cohort studies on associations
between insomnia and multiple health outcomes. Study design An umbrella review of meta …

Insomnia, sleep duration, and risk of anxiety: A two-sample Mendelian randomization study

F Zhou, S Li, H Xu - Journal of psychiatric research, 2022 - Elsevier
Background The effect of insomnia and sleep duration on risk of anxiety has been assessed
based on traditional epidemiological studies. However, the inconsistent conclusions do not …

Factors associated with healthcare workers' insomnia symptoms and fatigue in the fight against COVID-19, and the role of organizational support

X Zou, S Liu, J Li, W Chen, J Ye, Y Yang, F Zhou… - Frontiers in …, 2021 - frontiersin.org
Background: Healthcare workers (HCWs) have been exposed to increased risks of insomnia
and fatigue during the COVID-19 pandemic. In this study, we identify important risk factors …

Niosomes for nose-to-brain delivery: a non-invasive versatile carrier system for drug delivery in neurodegenerative diseases

AR Al Jayoush, HAFM Hassan, H Asiri, M Jafar… - Journal of Drug Delivery …, 2023 - Elsevier
Neurodegenerative diseases (NDDs) significantly contribute to morbidity and mortality
worldwide. The suboptimal effect of currently used therapeutic approaches administered via …

Independent and combined associations of sleep duration and sleep quality with common physical and mental disorders: results from a multi-ethnic population-based …

LSE Seow, XW Tan, SA Chong, JA Vaingankar… - PLoS …, 2020 - journals.plos.org
Sleep duration and sleep quality are often linked to increased risk of mortality and morbidity.
However, national representative data on both sleep duration and sleep quality and their …